PDB entry 7ela

View 7ela on RCSB PDB site
Description: structure of lassa virus polymerase in complex with 3'-vrna and z mutant (f36a)
Deposited on 2021-04-09, released 2021-05-05
The last revision was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: EM
Resolution: 3.4 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RNA-directed RNA polymerase L
    Species: Lassa mammarenavirus [TaxId:11620]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: RING finger protein Z
    Species: Lassa mammarenavirus [TaxId:11620]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A097F4I8 (0-98)
      • engineered mutation (35)
  • Chain 'C':
    Compound: 3-'vRNA promoter
    Species: Lassa mammarenavirus, synthetic [TaxId:11620]
  • Heterogens: MN, ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7elaA (A:)
meediacvkdlvskylannerlsrqklaflvqteprmllmeglkllslcievdscnangc
ehnsedksverilhdhgvltpslcfvvpdgykltgnvlillecfvrsspanfeqkyvedf
kkleqlkedlksvdinliplidgrtsfyneqipdwvndklrdtlfsllkyaqesnslfee
seysrlceslsmtsgrlsgveslnalldnrsnhyeeviaschqginnkltahevklqiee
eyqvfrnrlrkgeiegqflkveknqllnefnnlyadkvaekdsvehlthqfkraspilrf
lyaniskgdngegnliigecqmqcwrsflnkvksmrilntrrklllifdalillaskhdq
vrkkplrgwlgtcfvsvndrlvslestkkdlkkwverrqqversrtmqsfqcpsknqiln
sifqktiskattalrdvgisvdhykidmevicpdgydlimdfdvsgvtptisyqrseeea
fpyimgdvdllkttdlerlsslslalvnsmktsstvklrqnefgparyqvvkckeaycqe
fslgetefqliyqktgecskcyaindnrvgevcsfyadpkryfpaifsaevlqttvstmi
swiedcneleeqldkirsltkmilililahpskrsqkllqnlryfimayvsdyyhkdlid
kvreelitdvefllyrllrtlmglvlsedvksmmtnrfkfilnisymchfitketpdrlt
dqikcfekflepkvkfghvsinpadtateeelddmvynakkflskggctsakgpsykkpg
vskkylslltssfnngslfkerevkkeikdplitsgcataldlasnksvvvnkytdgsrv
lnydfnkltalavsqltevfsrkgkhllnkqdyeykvqqamsnlvlgskqhkgdadeadl
deilldggastyfnqlketvekivdqyrepvkmgsgsndgdqpsindldeivsnkfyirl
ikgelsnhmvedfdhdvlpdkfyeefcdavyensklkekyfycghmsqcpigeltkavst
rtyldheyfqcfksillimnanalmgkythyksrnlnfkfdmgklsddariseresnsea
lskalsltncttamlknlcfysqespqsynsvgpdtgrlkfslsykeqvggnrelyigdl
rtkmftrliedyfealssqlsgsclnnekefenailsmklnvsmahvsysmdhskwgpmm
cpflfltvlqnliflskdlqadikgrdylstllmwhmhkmveipfnvvsammksfikaql
glrkktkqsitedffysnfqigvvpshissildmgqgilhntsdfyaliterfinyaisc
vcggtidaytssddqislfdqtltellhrdpeefralmefhyymsdqlnkfvspksvigr
fvaefksrffvwgdevplltkfvaaalhnikckephqlaetidtivdqsvangvpvhlcn
liqirtlsllqyarypidpfllncetdvrdwvdgnrsyrimrqieglipdacskirsmlr
rlynrlktgqlheefttnylssehlsslknlcellgveppsesdleyswlnlaahhplrm
vlrqkiiysgavnlddekiptivktiqnklsstftrgaqkllseainksafqssiasgfv
glcrtlgskcvrgpnkenlyiksiqslitgtqgielltnsigvqywrvplglrnksesvv
syfrpllwdymcislstaielgawvlgdpkttkaldffkhnpcdyfplkptasklledrv
glnhiihslrrlypsvfekhilpfmsdlastkmkwsprikfldlcvaldvncealslvsh
ivkwkreehyivlsselrfshtrthepmveervvstsdavdnfmrqiyfesyvrpfvatt
rtlgsftwfphrtsipegeglhrlgpfssfvekvihkgverpmfkhdlmmgyawidfdie
parfnqnqliasglvdskfdsledffdavaslptgsaklsqtvrfriksqdasfresfai
hldyigsmnqqakylvhdvtamysgavspcvlsdcwrlvlsgptfkgkpvwyvdtevine
flvdtnqlghvtpvevvvdmeklqfaeydfmlvgpcaepvplvvrrgglwecekklasft
pviqdqdlemfvrevgdtssdlliralsdmitdrlglrmqwsgvdivstlraaapgnaev
lsavlevvdnwvefkgyalcysksrgrvmvqsssgklrlkgrtceelteggehvedie

    Sequence, based on observed residues (ATOM records):
    >7elaA (A:)
meediacvkdlvskylannerlsrqklaflvqteprmllmeglkllslcievdscnangc
ehnsedksverilhdhgvltpslcfvvpdgykltgnvlillecfvrsspanfeqkyvedf
kkleqlkedlksvdinliplidgrtsfyneqipdwvndklrdtlfsllkyaqesnslfee
seysrlceslsmteslnalldnrsnhyeeviaschqginnkltahevklqieeeyqvfrn
rlrkgeiegqflkveknqllnefnnlyadkvaekdsvehlthqfkraspilrflyanise
cqmqcwrsflnkvksmrilntrrklllifdalillaskhdqvrkkplrgwlgtcfvsvnd
rlvslestkkdlkkwverrqqvecpsknqilnsifqktiskattalrdvgisvdhykidm
evicpdgydlimdfdvsgvtptisyqrseeeafpyimgdvdllkttdlerlsslslalvn
smktsstvkeaycqefslgetefqliyqktgecskcyaindnrvgevcsfyadpkryfpa
ifsaevlqttvstmiswiedcneleeqldkirsltkmilililahpskrsqkllqnlryf
imayvsdyyhkdlidkvreelitdvefllyrllrtlmglvlsedvksmmtnrfkfilnis
ymchfitketpdrltdqikcfekflepkvkfghvsinpadtateeelddmvynakkflsk
ggctsakgpsykkpgvskkylslltssfnngslfkqespqsynsvgpdtgrlkfslsyke
qvggnrelyigdlrtkmftrliedyfealssqlsgsclnnekefenailsmklnvsmahv
sysmdhskwgpmmcpflfltvlqnliflsikgrdylstllmwhmhkmveipfnvvsammk
sfikaqlgtkqsitedffysnfqigvvpshissildmgqgilhntsdfyaliterfinya
iscvcggtidaytssddqislfdqtltellhrdpeefralmefhyymsdqlnkfvspksv
igrfvaefksrffvwgdevplltkfvaaalhnikckephqlaetidtivdqsvangvpvh
lcnliqirtlsllqyarypidpfllncetdvrdwvdgnrsyrimrqieglipdacskirs
mlrrlynrlktgqlheefttnylssehlsslknlcellgveppsesdleyswlnlaahhp
lrmviptivktiqnssiasgfvglcrtlgskcvrgpnkenlyiksiqslitgtqgiellt
nsigvqywrvplglrnksesvvsyfrpllwdymcislstaielgawvlgdpkttnpcdyf
plkptasklledrvglnhiihslrrlypsvfekhilikfldlcvaldvncealslvshiv
kwkreehyivlsselrfshtrt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7elaB (B:)
mgnkqvkapearnspraslipdathlgpqfckscwaenkglvecnnhylclncltlllgv
ssrcpickmplptrlrpsaaptappaeagdntrpppysp

    Sequence, based on observed residues (ATOM records):
    >7elaB (B:)
hlgpqfckscwaenkglvecnnhylclncltlllgvssrcpickmplpt

  • Chain 'C':
    No sequence available.