PDB entry 7egh

View 7egh on RCSB PDB site
Description: tfiid lobe c subcomplex
Deposited on 2021-03-24, released 2021-05-12
The last revision was dated 2021-05-12, with a file datestamp of 2021-05-07.
Experiment type: EM
Resolution: 3.04 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transcription initiation factor TFIID subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TAF1, BA2R, CCG1, CCGS, TAF2A
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: transcription initiation factor tfiid subunit 2
    Species: Homo sapiens [TaxId:9606]
    Gene: TAF2, CIF150, TAF2B
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: transcription initiation factor tfiid subunit 6
    Species: Homo sapiens [TaxId:9606]
    Gene: TAF6, TAF2E, TAFII70
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Transcription initiation factor TFIID subunit 7
    Species: Homo sapiens [TaxId:9606]
    Gene: TAF7, TAF2F, TAFII55
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Transcription initiation factor TFIID subunit 8
    Species: Homo sapiens [TaxId:9606]
    Gene: TAF8, TAFII43, TBN
    Database cross-references and differences (RAF-indexed):
  • Chain 'X':
    Compound: DNA (45-mer)
    Species: Homo sapiens [TaxId:9606]
  • Chain 'Y':
    Compound: DNA (45-mer)
    Species: Homo sapiens [TaxId:9606]
  • Chain 'f':
    Compound: transcription initiation factor tfiid subunit 6
    Species: Homo sapiens [TaxId:9606]
    Gene: TAF6, TAF2E, TAFII70
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7eghA (A:)
mgpgcdlllrtaatitaaaimsdtdsdedsagggpfslagflfgningagqlegesvldd
eckkhlaglgalglgsliteltaneeltgtdgalvndegwvrstedavdysdinevaede
srryqqtmgslqplchsdydeddydadcedidcklmpppppppgpmkkdkdqdsitgekv
dfssssdsesemgpqeatqaesedgkltlplagimqhdatkllpsvtelfpefrpgkvlr
flrlfgpgknvpsvwrsarrkrkkkhreliqeeqiqevecsvesevsqkslwnydyappp
ppeqclsddeitmmapveskfsqstgdidkvtdtkprvaewrygparlwydmlgvpedgs
gfdygfklrktehepviksrmieefrkleenngtdlladenflmvtqlhweddiiwdged
vkhkgtkpqraslagwlpssmtrnamaynvqqgfaatldddkpwysifpidnedlvygrw
edniiwdaqamprlleppvltldpndenlileipdekeeatsnspskeskkesslkksri
llgktgvikeepqqnmsqpevkdpwnlsndeyyypkqqglrgtfggniiqhsipavelrq
pffpthmgpiklrqfhrpplkkysfgalsqpgphsvqpllkhikkkakmreqerqasggg
emffmrtpqdltgkdgdlilaeyseengplmmqvgmatkiknyykrkpgkdpgapdckyg
etvychtspflgslhpgqllqafennlfrapiylhkmpetdfliirtrqgyyirelvdif
vvgqqcplfevpgpnskranthirdflqvfiyrlfwkskdrprrirmedikkafpshses
sirkrlklcadfkrtgmdsnwwvlksdfrlpteeeiramvspeqccayysmiaaeqrlkd
agygeksffapeeeneedfqmkiddevrtapwnttrafiaamkgkcllevtgvadptgcg
egfsyvkipnkptqqkddkepqpvkktvtgtdadlrrlslknakqllrkfgvpeeeikkl
srwevidvvrtmsteqarsgegpmskfargsrfsvaehqerykeecqrifdlqnkvlsst
evlstdtdsssaedsdfeemgknienmlqnkktssqlsrereeqerkelqrmllaagsaa
sgnnhrdddtasvtslnssatgrclkiyrtfrdeegkeyvrcetvrkpavidayvrirtt
kdeefirkfalfdeqhreemrkerrriqeqlrrlkrnqekeklkgppekkpkkmkerpdl
klkcgacgaighmrtnkfcplyyqtnappsnpvamteeqeeelektvihndneelikveg
tkivlgkqliesadevrrkslvlkfpkqqlppkkkrrvgttvhcdylnrphksihrrrtd
pmvtlssilesiindmrdlpntypfhtpvnakvvkdyykiitrpmdlqtlrenvrkrlyp
sreefrehlelivknsatyngpkhsltqisqsmldlcdeklkekedklarlekainplld
dddqvafsfildnivtqkmmavpdswpfhhpvnkkfvpdyykvivnpmdletirkniskh
kyqsresflddvnlilansvkyngpesqytktaqeivnvcyqtlteydehltqlekdict
akeaaleeaelesldpmtpgpytpqppdlydtntslsmsrdasvfqdesnmsvldipsat
pekqvtqegedgdgdladeeegtvqqpqasvlyedllmsegeddeedagsdeegdnpfsa
iqlsesgsdsdvgsggirpkqprmlqentrmdmeneesmmsyegdggeashgledsnisy
gsyeepdpksntqdtsfssiggyevseeeedeeeeeqrsgpsvlsqvhlsedeedsedfh
siagdsdldsde

    Sequence, based on observed residues (ATOM records):
    >7eghA (A:)
dtkprvaewrygparlwydmlgvpedgsdlladenflmvtqlhweddiiwdgepwysifp
idnedlvygrwedniiwdaqamprlleppvltldpndenlilpwnlsndeyyypkiiqhs
ipavelrqpffpthmgpiklrqfhrpplkkysfgalsqpgphsvqpllkhikkkakmreq
erqasgggemffmrtpqdltgkdgdlilaeyseengplmmqvgmatkiknyykrkpgkdp
gapdckygetvychtspflgslhpgqllqafennlfrapiylhkmpetdfliirtrqgyy
irelvdifvvgqqcplfevpgpnskranthirdflqvfiyrlfwkskdrprrirmedikk
afpshsessirkrlklcadfkrtgmdsnwwvlksdfrlpteeeiramvspeqccayysmi
aaeqrlkdagddevrtapwnttrafiaamkgkcllevtgvadptgcgegfsyvkipnkda
dlrrlslknakqllrkfgvpeeeikklsrwevidvvrtmsterfsvaehqerykeecqri
fdlqnkvlsstevlstdatgrclkiyrtfrdeegkeyvrcetvrkpavidayvrirttkd
eefhreemrkerrriqeqlrrlkrnqekek

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7eghB (B:)
mpltgveparmnrkkgdkgfesprpyklthqvvcinninfqrksvvgfveltifptvanl
nriklnskqcriyrvrindleaafiyndptlevchseskqrnlnyfsnayaaavsavdpd
agngelcikvpselwkhvdelkvlkihinfsldqpkgglhfvvpsvegsmaergahvfsc
gyqnstrfwfpcvdsyselctwkleftvdaamvavsngdlvetvythdmrkktfhymlti
ptaasnislaigpfeilvdpymhevthfclpqllpllkhttsylhevfefyeeiltcryp
yscfktvfideayvevaayasmsifstnllhsamiidetpltrrclaqslaqqffgcfis
rmswsdewvlkgisgyiyglwmkktfgvneyrhwikeeldkivayelktggvllhpifgg
gkekdnpashlhfsikhphtlsweyysmfqckahlvmrlienrismefmlqvfnkllsla
stassqkfqshmwsqmlvstsgflksisnvsgkdiqplikqwvdqsgvvkfygsfafnrk
rnvleleikqdytspgtqkyvgplkvtvqeldgsfnhtlqieenslkhdipchsksrrnk
kkkiplmngeevdmdlsamdadspllwiridpdmsvlrkvefeqadfmwqyqlryerdvv
aqqesilalekfptpasrlaltdileqeqcfyrvrmsacfclakiansmvstwtgppamk
slftrmfcckscpnivktnnfmsfqsyflqktmpvamallrdvhnlcpkevltfildlik
yndnrknkfsdnyyraemidalansvtpavsvnnevrtldnlnpdvrlileeitrflnme
kllpsyrhtitvsclrairvlqknghvpsdpalfksyaeyghfvdiriaaleavvdytkv
drsyeelqwllnmiqndpvpyvrhkilnmltknppftknmesplcnealvdqlwklmnsg
tshdwrlrcgavdlyftlfglsrpsclplpelglvlnlkekkavlnptiipesvagnqea
annpsshpqlvgfqnpfsssqdeeeidmdtvhdsqafishhlnmlerpstpglskyrpas
srsalipqhsagcdstpttkpqwslelarkgtgkeqaplemsmhpaasaplsvftkesta
skhsdhhhhhhhehkkkkkkhkhkhkhkhkhdskekdkepftfsspasgrsirspslsd

    Sequence, based on observed residues (ATOM records):
    >7eghB (B:)
gfesprpyklthqvvcinninfqrksvvgfveltifptvanlnriklnskqcriyrvrin
dleaafiyndptlevchseskqrnlnyfsnayaaavsavdpdagngelcikvpselwkhv
delkvlkihinfsldqpkgglhfvvpsvegsmaergahvfscgyqnstrfwfpcvdsyse
lctwkleftvdaamvavsngdlvetvythdmrkktfhymltiptaasnislaigpfeilv
dpymhevthfclpqllpllkhttsylhevfefyeeiltcrypyscfktvfideayvevaa
yasmsifstnllhsamiidetpltrrclaqslaqqffgcfisrmswsdewvlkgisgyiy
glwmkktfgvneyrhwikeeldkivayelktggvllhpifnpashlhfsikhphtlswey
ysmfqckahlvmrlienrismefmlqvfnkllslastassqkfqshmwsqmlvstsgflk
sisnvsgkdiqplikqwvdqsgvvkfygsfafnrkrnvleleikqdytspgtqkyvgplk
vtvqeldgsfnhtlqieenslkhdipchsksrrnkkkkiplmngeevdmdlsamdadspl
lwiridpdmsvlrkvefeqadfmwqyqlryerdvvaqqesilalekfptpasrlaltdil
eqeqcfyrvrmsacfclakiansmvstwtgppamkslftrmfcckscpnivktnnfmsfq
syflqktmpvamallrdvhnlcpkevltfildlikyndnrknkfsdnyyraemidalans
vtpavsvnnevrtldnlnpdvrlileeitrflnmekllpsyrhtitvsclrairvlqkng
hvpsdpalfksyaeyghfvdiriaaleavvdytkvdrsyeelqwllnmiqndpvpyvrhk
ilnmltknppftknmesplcnealvdqlwklmnsgtshdwrlrcgavdlyftlfglsrps
clp

  • Chain 'F':
    Sequence, based on SEQRES records:
    >7eghF (F:)
maeekklklsntvlpsesmkvvaesmgiaqiqeetcqlltdevsyrikeiaqdalkfmhm
gkrqklttsdidyalklknveplygfhaqefipfrfasgggrelyfyeekevdlsdiint
plprvpldvclkahwlsiegcqpaipenpppapkeqqkaeateplksakpgqeedgplkg
kgqgattadgkgkekkappllegaplrlkprsihelsveqqlyykeiteacvgsceakra
ealqsiatdpglyqmlprfstfisegvrvnvvqnnlalliylmrmvkalmdnptlyleky
vhelipavmtcivsrqlclrpdvdnhwalrdfaarlvaqickhfstttnniqsritktft
kswvdektpwttrygsiaglaelghdviktlilprlqqegerirsvldgpvlsnidriga
dhvqslllkhcapvlaklrpppdnqdayraefgslgpllcsqvvkaraqaalqaqqvnrt
tltitqprptltlsqapqpgprtpgllkvpgsialpvqtlvsaraaappqpsppptkfiv
msssssapstqqvlslstsapgsgstttspvtttvpsvqpivklvstattappstapsgp
gsvqkyivvslpptgegkggptshpspvpppasspsplsgsalcggkqeagdspppapgt
pkangsqpnsgspqpap

    Sequence, based on observed residues (ATOM records):
    >7eghF (F:)
rlkprsihelsveqqlyykeiteacvgsceakraealqsiatdpglyqmlprfstfiseg
vrvnvvqnnlalliylmrmvkalmdnptlylekyvhelipavmtcivsrqlclrpdvdnh
walrdfaarlvaqickhfstttnniqsritktftkswvdektpwttrygsiaglaelghd
viktlilprlqqegerirsvldgpvlsnidrigadhvqslllkhcapvlaklrpppdnqd
ayraefgslgpllcsqvvkaraqaalq

  • Chain 'G':
    Sequence, based on SEQRES records:
    >7eghG (G:)
mskskddaphelesqfilrlppeyastvrravqsghvnlkdrltielhpdgrhgivrvdr
vplasklvdlpcvmeslktidkktfyktadicqmlvstvdgdlyppveepvastdpkask
kkdkdkekkfiwnhgitlplknvrkrrfrktakkkyiespdvekevkrllstdaeavstr
weiiaedetkeaenqgldisspgmsghrqghdslehdelreifndlssssededetqhqd
eediniidteedlerqlqdklnesdeqhqenegtnqlvmgiqkqidnmkgklqetqdrak
rqedlimkvenlalknrfqavldelkqkedrekeqlsslqeelesllek

    Sequence, based on observed residues (ATOM records):
    >7eghG (G:)
phelesqfilrlppeyastvrravqsghvnlkdrltielhpdgrhgivrvdrvplasklv
dlpcvmeslktidkktfyktadicqmlvstekkfiwnhgitlplknvrkrrfrktakdve
kevkrllstdaeavstrweiiaed

  • Chain 'H':
    Sequence, based on SEQRES records:
    >7eghH (H:)
madaaatagaggsgtrsgskqstnpadnyhlarrrtlqvvvssllteagfesaekasvet
ltemlqsyiseigrsaksycehtartqptlsdivvtlvemgfnvdtlpayakrsqrmvit
appvtnqpvtpkaltagqnrphpphipshfpefpdphtyiktptyrepvsdyqvlrekaa
sqrrdveraltrfmaktgetqslfkddvstfpliaarpftipyltallpselemqqmeet
dsseqdeqtdtenlalhismedsgaekentsvlqqnpslsgsrngeeniidnpylrpvkk
pkirrkksls

    Sequence, based on observed residues (ATOM records):
    >7eghH (H:)
ktptyrepvsdyqvlrekaasqrrdveraltrfmaktgetqslfkddvstfpliaarpft
ipyltallpsel

  • Chain 'X':
    No sequence available.

  • Chain 'Y':
    No sequence available.

  • Chain 'f':
    Sequence, based on SEQRES records:
    >7eghf (f:)
maeekklklsntvlpsesmkvvaesmgiaqiqeetcqlltdevsyrikeiaqdalkfmhm
gkrqklttsdidyalklknveplygfhaqefipfrfasgggrelyfyeekevdlsdiint
plprvpldvclkahwlsiegcqpaipenpppapkeqqkaeateplksakpgqeedgplkg
kgqgattadgkgkekkappllegaplrlkprsihelsveqqlyykeiteacvgsceakra
ealqsiatdpglyqmlprfstfisegvrvnvvqnnlalliylmrmvkalmdnptlyleky
vhelipavmtcivsrqlclrpdvdnhwalrdfaarlvaqickhfstttnniqsritktft
kswvdektpwttrygsiaglaelghdviktlilprlqqegerirsvldgpvlsnidriga
dhvqslllkhcapvlaklrpppdnqdayraefgslgpllcsqvvkaraqaalqaqqvnrt
tltitqprptltlsqapqpgprtpgllkvpgsialpvqtlvsaraaappqpsppptkfiv
msssssapstqqvlslstsapgsgstttspvtttvpsvqpivklvstattappstapsgp
gsvqkyivvslpptgegkggptshpspvpppasspsplsgsalcggkqeagdspppapgt
pkangsqpnsgspqpap

    Sequence, based on observed residues (ATOM records):
    >7eghf (f:)
helsveqqlyykeiteacvgsceakraealqsiatdpglyqmlprfstfisegvrvnvvq
nnlalliylmrmvkalmdnptlylekyvhelipavmtcivsrqlclrpdvdnhwalrdfa
arlvaqickhfstttnniqsritktftkswvdektpwttrygsiaglaelghdviktlil
prlqqegerirsvldgpvlsnidrigadhvqslllkhcapvlaklrpppdnqdayraefg
slgpllcsqvvkaraqaalq