PDB entry 7e8m

View 7e8m on RCSB PDB site
Description: Crystal structure of SARS-CoV-2 antibody P2C-1F11 with mutated RBD
Class: viral protein/immune system
Keywords: SARS-CoV-2 spike, receptor binding domain, antibody, VIRAL PROTEIN, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2021-03-02, released 2021-05-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-26, with a file datestamp of 2021-05-21.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'E':
    Compound: Spike protein S1
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2 (0-194)
      • engineered mutation (84)
      • engineered mutation (151)
      • engineered mutation (168)
    Domains in SCOPe 2.08: d7e8me_
  • Chain 'H':
    Compound: antibody P2C-1F11 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7E8M (Start-216)
    Domains in SCOPe 2.08: d7e8mh_
  • Chain 'L':
    Compound: antibody P2C-1F11 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7E8M (0-213)
    Domains in SCOPe 2.08: d7e8ml1, d7e8ml2
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7e8mE (E:)
tnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcf
tnvyadsfvirgdevrqiapgqtgniadynyklpddftgcviawnsnnldskvggnynyl
yrlfrksnlkpferdisteiyqagstpcngvkgfncyfplqsygfqptygvgyqpyrvvv
lsfellhapatvcgp

    Sequence, based on observed residues (ATOM records): (download) 
    >7e8mE (E:)
tnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcf
tnvyadsfvirgdevrqiapgqtgniadynyklpddftgcviawnsnnldskvggnynyl
yrlfrksnlkpferdisteiyqagstpcngvkgfncyfplqsygfqptygvgyqpyrvvv
lsfeapatvcgp

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >7e8mH (H:)
evqlvesggglvqpggslrlscaasgitvssnymnwvrqapgkglewvsliysggstyya
dsvkgrftisrdnskntlylqmnslraedtavyhcardlvvygmdvwgqgttvtvssast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

    Sequence, based on observed residues (ATOM records): (download) 
    >7e8mH (H:)
vqlvesggglvqpggslrlscaasgitvssnymnwvrqapgkglewvsliysggstyyad
svkgrftisrdnskntlylqmnslraedtavyhcardlvvygmdvwgqgttvtvssastk
gpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvt
vpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7e8mL (L:)
eivltqspgtlsispgeratlscrasqsvsssylawyqqkpgqaprlliygassratgip
drfsgsgsgtdftltisrlepedfavyycqqygssptfgqgtkleikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec