PDB entry 7e4t

View 7e4t on RCSB PDB site
Description: human trpc5 apo state structure at 3 angstrom
Deposited on 2021-02-15, released 2021-03-31
The last revision was dated 2021-10-13, with a file datestamp of 2021-10-08.
Experiment type: EM
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Short transient receptor potential channel 5
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPC5, TRP5
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Short transient receptor potential channel 5
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPC5, TRP5
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Short transient receptor potential channel 5
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPC5, TRP5
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Short transient receptor potential channel 5
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPC5, TRP5
    Database cross-references and differences (RAF-indexed):
  • Heterogens: PTY, POV, Y01, ZN, CA, YZY

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7e4tA (A:)
maqlyykkvnyspyrdriplqivraetelsaeekaflnavekgdyatvkqalqeaeiyyn
vnincmdplgrsalliaienenleimelllnhsvyvgdallyairkevvgavelllsyrr
psgekqvptlmmdtqfseftpditpimlaahtnnyeiikllvqkrvtiprphqircncve
cvsssevdslrhsrsrlniykalaspslialssedpiltafrlgwelkelskvenefkae
yeelsqqcklfakdlldqarssreleiilnhrddhseeldpqkyhdlaklkvaikyhqke
fvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigflfpmlsiaylisprsnlglfi
kkpfikfichtasyltflfmlllasqhivrtdlhvqgppptvvewmilpwvlgfiwgeik
emwdggfteyihdwwnlmdfamnslylatislkivayvkyngsrpreewemwhptliaea
lfaisnilsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyf
yyetraidepnnckgircekqnnafstlfetlqslfwsvfgllnlyvtnvkarheftefv
gatmfgtynvislvvllnmliammnnsyqliadhadiewkfartklwmsyfdeggtlppp
fniipspksflylgnwfnntfcpkrdpdgrrrrrnlrsfternadsliqnqhyqevirnl
vkryvaamirnsktheglteenfkelkqdissfryevldllgnr

    Sequence, based on observed residues (ATOM records):
    >7e4tA (A:)
riplqivraetelsaeekaflnavekgdyatvkqalqeaeiyynvnincmdplgrsalli
aienenleimelllnhsvyvgdallyairkevvgavelllsyqfseftpditpimlaaht
nnyeiikllvqkrvtiprphqircncvecvsssevdslrhsrsrlniykalaspslials
sedpiltafrlgwelkelskvenefkaeyeelsqqcklfakdlldqarssreleiilnhr
ddlaklkvaikyhqkefvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigflfpml
siaylisprsnlglfikkpfikfichtasyltflfmlllasqdlhvqgppptvvewmilp
wvlgfiwgeikemwdggfteyihdwwnlmdfamnslylatislkivayvkyngsrpreew
emwhptliaealfaisnilsslrlislftanshlgplqislgrmlldilkflfiyclvll
afanglnqlyfyyetraidepnnckgircekqnnafstlfetlqslfwsvfgllnlyvtn
vkarheftefvgatmfgtynvislvvllnmliammnnsyqliadhadiewkfartklwms
yfdeggtlpppfniisliqnqhyqevirnlvkryvaamirnteenfkelkqdissfryev
ldll

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7e4tB (B:)
maqlyykkvnyspyrdriplqivraetelsaeekaflnavekgdyatvkqalqeaeiyyn
vnincmdplgrsalliaienenleimelllnhsvyvgdallyairkevvgavelllsyrr
psgekqvptlmmdtqfseftpditpimlaahtnnyeiikllvqkrvtiprphqircncve
cvsssevdslrhsrsrlniykalaspslialssedpiltafrlgwelkelskvenefkae
yeelsqqcklfakdlldqarssreleiilnhrddhseeldpqkyhdlaklkvaikyhqke
fvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigflfpmlsiaylisprsnlglfi
kkpfikfichtasyltflfmlllasqhivrtdlhvqgppptvvewmilpwvlgfiwgeik
emwdggfteyihdwwnlmdfamnslylatislkivayvkyngsrpreewemwhptliaea
lfaisnilsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyf
yyetraidepnnckgircekqnnafstlfetlqslfwsvfgllnlyvtnvkarheftefv
gatmfgtynvislvvllnmliammnnsyqliadhadiewkfartklwmsyfdeggtlppp
fniipspksflylgnwfnntfcpkrdpdgrrrrrnlrsfternadsliqnqhyqevirnl
vkryvaamirnsktheglteenfkelkqdissfryevldllgnr

    Sequence, based on observed residues (ATOM records):
    >7e4tB (B:)
riplqivraetelsaeekaflnavekgdyatvkqalqeaeiyynvnincmdplgrsalli
aienenleimelllnhsvyvgdallyairkevvgavelllsyqfseftpditpimlaaht
nnyeiikllvqkrvtiprphqircncvecvsssevdslrhsrsrlniykalaspslials
sedpiltafrlgwelkelskvenefkaeyeelsqqcklfakdlldqarssreleiilnhr
ddlaklkvaikyhqkefvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigflfpml
siaylisprsnlglfikkpfikfichtasyltflfmlllasqdlhvqgppptvvewmilp
wvlgfiwgeikemwdggfteyihdwwnlmdfamnslylatislkivayvkyngsrpreew
emwhptliaealfaisnilsslrlislftanshlgplqislgrmlldilkflfiyclvll
afanglnqlyfyyetraidepnnckgircekqnnafstlfetlqslfwsvfgllnlyvtn
vkarheftefvgatmfgtynvislvvllnmliammnnsyqliadhadiewkfartklwms
yfdeggtlpppfniisliqnqhyqevirnlvkryvaamirnteenfkelkqdissfryev
ldll

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7e4tC (C:)
maqlyykkvnyspyrdriplqivraetelsaeekaflnavekgdyatvkqalqeaeiyyn
vnincmdplgrsalliaienenleimelllnhsvyvgdallyairkevvgavelllsyrr
psgekqvptlmmdtqfseftpditpimlaahtnnyeiikllvqkrvtiprphqircncve
cvsssevdslrhsrsrlniykalaspslialssedpiltafrlgwelkelskvenefkae
yeelsqqcklfakdlldqarssreleiilnhrddhseeldpqkyhdlaklkvaikyhqke
fvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigflfpmlsiaylisprsnlglfi
kkpfikfichtasyltflfmlllasqhivrtdlhvqgppptvvewmilpwvlgfiwgeik
emwdggfteyihdwwnlmdfamnslylatislkivayvkyngsrpreewemwhptliaea
lfaisnilsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyf
yyetraidepnnckgircekqnnafstlfetlqslfwsvfgllnlyvtnvkarheftefv
gatmfgtynvislvvllnmliammnnsyqliadhadiewkfartklwmsyfdeggtlppp
fniipspksflylgnwfnntfcpkrdpdgrrrrrnlrsfternadsliqnqhyqevirnl
vkryvaamirnsktheglteenfkelkqdissfryevldllgnr

    Sequence, based on observed residues (ATOM records):
    >7e4tC (C:)
riplqivraetelsaeekaflnavekgdyatvkqalqeaeiyynvnincmdplgrsalli
aienenleimelllnhsvyvgdallyairkevvgavelllsyqfseftpditpimlaaht
nnyeiikllvqkrvtiprphqircncvecvsssevdslrhsrsrlniykalaspslials
sedpiltafrlgwelkelskvenefkaeyeelsqqcklfakdlldqarssreleiilnhr
ddlaklkvaikyhqkefvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigflfpml
siaylisprsnlglfikkpfikfichtasyltflfmlllasqdlhvqgppptvvewmilp
wvlgfiwgeikemwdggfteyihdwwnlmdfamnslylatislkivayvkyngsrpreew
emwhptliaealfaisnilsslrlislftanshlgplqislgrmlldilkflfiyclvll
afanglnqlyfyyetraidepnnckgircekqnnafstlfetlqslfwsvfgllnlyvtn
vkarheftefvgatmfgtynvislvvllnmliammnnsyqliadhadiewkfartklwms
yfdeggtlpppfniisliqnqhyqevirnlvkryvaamirnteenfkelkqdissfryev
ldll

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7e4tD (D:)
maqlyykkvnyspyrdriplqivraetelsaeekaflnavekgdyatvkqalqeaeiyyn
vnincmdplgrsalliaienenleimelllnhsvyvgdallyairkevvgavelllsyrr
psgekqvptlmmdtqfseftpditpimlaahtnnyeiikllvqkrvtiprphqircncve
cvsssevdslrhsrsrlniykalaspslialssedpiltafrlgwelkelskvenefkae
yeelsqqcklfakdlldqarssreleiilnhrddhseeldpqkyhdlaklkvaikyhqke
fvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigflfpmlsiaylisprsnlglfi
kkpfikfichtasyltflfmlllasqhivrtdlhvqgppptvvewmilpwvlgfiwgeik
emwdggfteyihdwwnlmdfamnslylatislkivayvkyngsrpreewemwhptliaea
lfaisnilsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyf
yyetraidepnnckgircekqnnafstlfetlqslfwsvfgllnlyvtnvkarheftefv
gatmfgtynvislvvllnmliammnnsyqliadhadiewkfartklwmsyfdeggtlppp
fniipspksflylgnwfnntfcpkrdpdgrrrrrnlrsfternadsliqnqhyqevirnl
vkryvaamirnsktheglteenfkelkqdissfryevldllgnr

    Sequence, based on observed residues (ATOM records):
    >7e4tD (D:)
riplqivraetelsaeekaflnavekgdyatvkqalqeaeiyynvnincmdplgrsalli
aienenleimelllnhsvyvgdallyairkevvgavelllsyqfseftpditpimlaaht
nnyeiikllvqkrvtiprphqircncvecvsssevdslrhsrsrlniykalaspslials
sedpiltafrlgwelkelskvenefkaeyeelsqqcklfakdlldqarssreleiilnhr
ddlaklkvaikyhqkefvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigflfpml
siaylisprsnlglfikkpfikfichtasyltflfmlllasqdlhvqgppptvvewmilp
wvlgfiwgeikemwdggfteyihdwwnlmdfamnslylatislkivayvkyngsrpreew
emwhptliaealfaisnilsslrlislftanshlgplqislgrmlldilkflfiyclvll
afanglnqlyfyyetraidepnnckgircekqnnafstlfetlqslfwsvfgllnlyvtn
vkarheftefvgatmfgtynvislvvllnmliammnnsyqliadhadiewkfartklwms
yfdeggtlpppfniisliqnqhyqevirnlvkryvaamirnteenfkelkqdissfryev
ldll