PDB entry 7e4l

View 7e4l on RCSB PDB site
Description: conversion of pyrophosphate-dependent myo-inositol-1 kinase into myo- inositol-3 kinase by n78l/s89l mutation
Deposited on 2021-02-14, released 2021-05-05
The last revision was dated 2021-06-02, with a file datestamp of 2021-05-28.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: PfkB domain-containing protein
    Species: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) [TaxId:243274]
    Gene: Tmari_0412
    Database cross-references and differences (RAF-indexed):
    • Uniprot R4NYE9 (0-285)
      • engineered mutation (77)
      • engineered mutation (88)
  • Chain 'B':
    Compound: PfkB domain-containing protein
    Species: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) [TaxId:243274]
    Gene: Tmari_0412
    Database cross-references and differences (RAF-indexed):
    • Uniprot R4NYE9 (0-285)
      • engineered mutation (77)
      • engineered mutation (88)
  • Heterogens: MDN, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7e4lA (A:)
mitfighvskdvnvvdgkreiaygggvvmgaitssllgvktkvitkctredvskfsflrd
ngvevvflksprttsielrygsdpdtrelflisaadpftesdlafiegeavhinplwyge
fpedlipvlrrkvmflsadaqgfvrvpeneklvyrdwemkekylkyldlfkvdsreaetl
tgtndlrescriirsfgakiilathasgvivfdgnfyeasfrswslegrtgrgdtctaaf
lvgfvfkkmsiekatkfaaavtsvkmrhpgplrredleaisgdqyf

    Sequence, based on observed residues (ATOM records):
    >7e4lA (A:)
mitfighvskdvnvvdgkreiaygggvvmgaitssllgvktkvitkctredvskfsflrd
ngvevvflksprttsielrelflisaadpftesdlafiegeavhinplwygefpedlipv
lrrkvmflsadaqgfvrvpeneklvyrdwemkekylkyldlfkvdsreaetltgtndlre
scriirsfgakiilathasgvivfdgnfyeasfrswslegrtgrgdtctaaflvgfvfkk
msiekatkfaaavtsvkmrhpgplrredleaisgdqyf

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7e4lB (B:)
mitfighvskdvnvvdgkreiaygggvvmgaitssllgvktkvitkctredvskfsflrd
ngvevvflksprttsielrygsdpdtrelflisaadpftesdlafiegeavhinplwyge
fpedlipvlrrkvmflsadaqgfvrvpeneklvyrdwemkekylkyldlfkvdsreaetl
tgtndlrescriirsfgakiilathasgvivfdgnfyeasfrswslegrtgrgdtctaaf
lvgfvfkkmsiekatkfaaavtsvkmrhpgplrredleaisgdqyf

    Sequence, based on observed residues (ATOM records):
    >7e4lB (B:)
mitfighvskdvnvvdgkreiaygggvvmgaitssllgvktkvitkctredvskfsflrd
ngvevvflksprttsielelflisaadpftesdlafiegeavhinplwygefpedlipvl
rrkvmflsadaqgfvrvpeneklvyrdwemkekylkyldlfkvdsreaetltgtndlres
criirsfgakiilathasgvivfdgnfyeasfrswslegrtgrgdtctaaflvgfvfkkm
siekatkfaaavtsvkmrhpgplrredleaisgdqyf