PDB entry 7dzx

View 7dzx on RCSB PDB site
Description: spike protein from sars-cov2 with fab fragment of enhancing antibody 8d2
Deposited on 2021-01-26, released 2021-06-02
The last revision was dated 2021-07-07, with a file datestamp of 2021-07-02.
Experiment type: EM
Resolution: 3.53 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2 (13-1133)
      • expression tag (0-12)
      • engineered mutation (600)
      • engineered mutation (668-669)
      • engineered mutation (671)
      • engineered mutation (972-973)
      • expression tag (1134-1248)
  • Chain 'B':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2 (13-1133)
      • expression tag (0-12)
      • engineered mutation (600)
      • engineered mutation (668-669)
      • engineered mutation (671)
      • engineered mutation (972-973)
      • expression tag (1134-1248)
  • Chain 'C':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2 (13-1133)
      • expression tag (0-12)
      • engineered mutation (600)
      • engineered mutation (668-669)
      • engineered mutation (671)
      • engineered mutation (972-973)
      • expression tag (1134-1248)
  • Chain 'H':
    Compound: Fab Heavy chain of enhancing antibody
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7DZX (0-226)
  • Chain 'L':
    Compound: Fab light chain of enhancing antibody
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7DZX (0-212)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7dzxA (A:)
qcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgt
ngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcef
qfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefv
fknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgd
sssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiy
qtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsas
fstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcv
iawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplq
sygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvlt
esnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyq
gvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecdipigagicas
yqtqtnspgsagsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtk
tsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktpp
ikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaq
kfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtq
nvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgai
ssvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecv
lgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpreg
vfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeld
kyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyikgs
grenlyfqggggsgyipeaprdgqayvrkdgewvllstflghhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >7dzxA (A:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpf
ndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyh
knnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiysk
htpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayy
vgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesi
vrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptk
lndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvg
gnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyq
pyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfg
rdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqgvnctevpvaiha
dqltptwrvystgsnvfqtragcligaehvnnsyecdipigagicasyqtqtnspgsags
vasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgds
tecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqil
pdpskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlppllt
demiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianq
fnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldp
peaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkg
yhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvtq
rnfyepqiittdntfvsgncdvvigivnntvydplqpelds

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7dzxB (B:)
qcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgt
ngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcef
qfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefv
fknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgd
sssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiy
qtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsas
fstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcv
iawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplq
sygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvlt
esnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyq
gvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecdipigagicas
yqtqtnspgsagsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtk
tsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktpp
ikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaq
kfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtq
nvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgai
ssvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecv
lgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpreg
vfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeld
kyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyikgs
grenlyfqggggsgyipeaprdgqayvrkdgewvllstflghhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >7dzxB (B:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpf
ndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyh
knnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiysk
htpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayy
vgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesi
vrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptk
lndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvg
gnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyq
pyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfg
rdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqgvnctevpvaiha
dqltptwrvystgsnvfqtragcligaehvnnsyecdipigagicasyqtqtnspgsags
vasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgds
tecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqil
pdpskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlppllt
demiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianq
fnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldp
peaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkg
yhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvtq
rnfyepqiittdntfvsgncdvvigivnntvydplqpelds

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7dzxC (C:)
qcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgt
ngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcef
qfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefv
fknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgd
sssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiy
qtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsas
fstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcv
iawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplq
sygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvlt
esnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyq
gvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecdipigagicas
yqtqtnspgsagsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtk
tsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktpp
ikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaq
kfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtq
nvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgai
ssvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecv
lgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpreg
vfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeld
kyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyikgs
grenlyfqggggsgyipeaprdgqayvrkdgewvllstflghhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >7dzxC (C:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpf
ndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyh
knnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiysk
htpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayy
vgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesi
vrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptk
lndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvg
gnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyq
pyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfg
rdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqgvnctevpvaiha
dqltptwrvystgsnvfqtragcligaehvnnsyecdipigagicasyqtqtnspgsags
vasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgds
tecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqil
pdpskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlppllt
demiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianq
fnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldp
peaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkg
yhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvtq
rnfyepqiittdntfvsgncdvvigivnntvydplqpelds

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >7dzxH (H:)
evqlvesggglvqpggslrlscaasgftfssywmswvrqapgkglewvaninqdgsekyy
vdsvkgrftisrdnaknslylqvnslraedtavyycardwdydiltgswfgafdiwgqgt
tvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records:
    >7dzxL (L:)
diqmtqspsslsasvgdrvtitcrasqgirndlgwyqqkpgkapkrliyaasslqsgvps
rfsgsgsgteftltisslqpedfatyyclqhnsypltfgggtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge