PDB entry 7dx9

View 7dx9 on RCSB PDB site
Description: trypsin-digested s protein of sars-cov-2 bound with pd of ace2 in the conformation 3 (3 up rbd and 2 pd bound)
Deposited on 2021-01-18, released 2021-03-31
The last revision was dated 2021-06-16, with a file datestamp of 2021-06-11.
Experiment type: EM
Resolution: 3.6 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (985-986)
  • Chain 'B':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (985-986)
  • Chain 'C':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (985-986)
  • Chain 'D':
    Compound: Angiotensin-converting enzyme 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2, UNQ868/PRO1885
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Angiotensin-converting enzyme 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2, UNQ868/PRO1885
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7dx9A (A:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqyikwpwyiwlgfiagliaivmvtimlccmtsccsclkgccscgscckfdedd
sepvlkgvklhytledykddddk

    Sequence, based on observed residues (ATOM records):
    >7dx9A (A:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhanpvlpfndgvyfasteksn
iirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvmesefrvyssannctf
eyvsknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtll
alhrsayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnf
rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfk
cygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawns
nnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfq
ptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkk
flpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnct
evpsnvfqtragcligaehvnnsyecdipigagicasyqtqsiiaytmslgaensvaysn
nsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltg
iaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvkfn
gltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvl
yenqklianqfnsaigkiqdslsalgklqdvvnqnaqalntlvkqlssnfgaissvlndi
lsrldppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrv
dfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngt
hwfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeld

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7dx9B (B:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqyikwpwyiwlgfiagliaivmvtimlccmtsccsclkgccscgscckfdedd
sepvlkgvklhytledykddddk

    Sequence, based on observed residues (ATOM records):
    >7dx9B (B:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhanpvlpfndgvyfasteksn
iirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvmesefrvyssannctf
eyvsknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtll
alhrsayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnf
rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfk
cygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawns
nnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfq
ptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkk
flpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnct
evpsnvfqtragcligaehvnnsyecdipigagicasyqtqsiiaytmslgaensvaysn
nsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltg
iaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvkfn
gltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvl
yenqklianqfnsaigkiqdslsalgklqdvvnqnaqalntlvkqlssnfgaissvlndi
lsrldppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrv
dfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngt
hwfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeld

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7dx9C (C:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqyikwpwyiwlgfiagliaivmvtimlccmtsccsclkgccscgscckfdedd
sepvlkgvklhytledykddddk

    Sequence, based on observed residues (ATOM records):
    >7dx9C (C:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhanpvlpfndgvyfasteksn
iirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvmesefrvyssannctf
eyvsknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtll
alhrsayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnf
rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfk
cygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawns
nnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfq
ptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkk
flpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnct
evpsnvfqtragcligaehvnnsyecdipigagicasyqtqsiiaytmslgaensvaysn
nsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltg
iaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvkfn
gltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvl
yenqklianqfnsaigkiqdslssalgklqdvvnqnaqalntlvkqlssnfgaissvlnd
ilsrldppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskr
vdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsng
thwfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeld

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7dx9D (D:)
masgrsssswlllslvavtaawshpqfekqstieeqaktfldkfnheaedlfyqsslasw
nyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalqqngssvl
sedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwawesw
rsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedveh
tfeeikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqk
pnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvqkavchpta
wdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeim
slsaatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgei
pkdqwmkkwwemkreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqea
lcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgaknmnvrpllnyf
eplftwlkdqnknsfvgwstdwspyadqsikvrislksalgdkayewndnemylfrssva
yamrqyflkvknqmilfgeedvrvanlkprisfnffvtapknvsdiiprtevekairmsr
srindafrlndnsleflgiqptlgppnqppvsiwlivfgvvmgvivvgiviliftgirdr
kkknkarsgenpyasidiskgennpgfqntddvqtsf

    Sequence, based on observed residues (ATOM records):
    >7dx9D (D:)
ieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstla
qmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnpqe
clllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedyg
dywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyispig
clpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvgl
pnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiq
ydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinfll
kqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycdp
aslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrl
gksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad

  • Chain 'E':
    Sequence, based on SEQRES records:
    >7dx9E (E:)
masgrsssswlllslvavtaawshpqfekqstieeqaktfldkfnheaedlfyqsslasw
nyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalqqngssvl
sedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwawesw
rsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedveh
tfeeikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqk
pnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvqkavchpta
wdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeim
slsaatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgei
pkdqwmkkwwemkreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqea
lcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgaknmnvrpllnyf
eplftwlkdqnknsfvgwstdwspyadqsikvrislksalgdkayewndnemylfrssva
yamrqyflkvknqmilfgeedvrvanlkprisfnffvtapknvsdiiprtevekairmsr
srindafrlndnsleflgiqptlgppnqppvsiwlivfgvvmgvivvgiviliftgirdr
kkknkarsgenpyasidiskgennpgfqntddvqtsf

    Sequence, based on observed residues (ATOM records):
    >7dx9E (E:)
ieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstla
qmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnpqe
clllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedyg
dywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyispig
clpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvgl
pnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiq
ydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinfll
kqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycdp
aslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrl
gksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad