PDB entry 7duo

View 7duo on RCSB PDB site
Description: Crystal structure of daratumumab fab and CD38 complex
Class: antitumor protein/hydrolase
Keywords: daratumumab, CD38, multiple myeloma, ANTIMICROBIAL PROTEIN, ANTITUMOR PROTEIN-HYDROLASE complex
Deposited on 2021-01-10, released 2021-03-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-03-10, with a file datestamp of 2021-03-05.
Experiment type: XRAY
Resolution: 2.81 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD38
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7duob_
  • Chain 'H':
    Compound: Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7DUO (0-End)
  • Chain 'L':
    Compound: Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7DUO (0-212)
    Domains in SCOPe 2.07: d7duol1, d7duol2

PDB Chain Sequences:

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7duoB (B:)
krfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcniteedyqplmklgtqt
vpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefntskinyqscpdw
rkdcsnnpvsvfwktvsrrfaeaacdvvhvmlngsrskifdknstfgsvevhnlqpekvq
tleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkfl

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7duoL (L:)
eivltqspatlslspgeratlscrasqsvssylawyqqkpgqaprlliydasnratgipa
rfsgsgsgtdftltisslepedfavyycqqrsnwpptfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge