PDB entry 7dtw

View 7dtw on RCSB PDB site
Description: human calcium-sensing receptor in the inactive close-close conformation
Deposited on 2021-01-06, released 2021-03-10
The last revision was dated 2021-04-14, with a file datestamp of 2021-04-09.
Experiment type: EM
Resolution: 4.5 Å
R-factor: N/A
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Extracellular calcium-sensing receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: CASR, GPRC2A, PCAR1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Extracellular calcium-sensing receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: CASR, GPRC2A, PCAR1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7dtwA (A:)
mktiialsyifclvfadykddddenlyfqgygpdqraqkkgdiilgglfpihfgvaakdq
dlksrpesvecirynfrgfrwlqamifaieeinsspallpnltlgyrifdtcntvskale
atlsfvaqnkidslnldefcncsehipstiavvgatgsgvstavanllglfyipqvsyas
ssrllsnknqfksflrtipndehqatamadiieyfrwnwvgtiaadddygrpgiekfree
aeerdicidfselisqysdeeeiqhvveviqnstakvivvfssgpdleplikeivrrnit
gkiwlaseawasssliampqyfhvvggtigfalkagqipgfreflkkvhprksvhngfak
efweetfnchlqegakgplpvdtflrgheesgdrfsnsstafrplctgdenissvetpyi
dythlrisynvylavysiahalqdiytclpgrglftngscadikkveawqvlkhlrhlnf
tnnmgeqvtfdecgdlvgnysiinwhlspedgsivfkevgyynvyakkgerlfineekil
wsgfsrevpfsncsrdclagtrkgiiegeptccfecvecpdgeysdetdasacnkcpddf
wsnenhtsciakeieflswtepfgialtlfavlgifltafvlgvfikfrntpivkatnre
lsylllfsllccfssslffigepqdwtcrlrqpafgisfvlciscilvktnrvllvfeak
iptsfhrkwwglnlqfllvflctfmqivicviwlytappssyrnqeledeiifitchegs
lmalgfligytcllaaicfffafksrklpenfneakfitfsmliffivwisfipayasty
gkfvsaveviailaasfgllaciffnkiyiilfkpsrntieevrcstaahafkvaaratl
rrsnvsrkrssslggstgstpsssissksnsedpfpqperqkqqqplaltqqeqqqqplt
lpqqqrsqqqprckqkvifgsgtvtfslsfdepqknamahrnsthqnsleaqkssdtltr
hepllplqcgetdldltvqetglqgpvggdqrpevedpeelspalvvsssqsfvisgggs
tvtenvvnshhhhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >7dtwA (A:)
gpdqraqkkgdiilgglfpihfgvaakdqdlksrpesvecirynfrgfrwlqamifaiee
insspallpnltlgyrifdtcntvskaleatlsfvaqnkidslnldefcncsehipstia
vvgatgsgvstavanllglfyipqvsyasssrllsnknqfksflrtipndehqatamadi
ieyfrwnwvgtiaadddygrpgiekfreeaeerdicidfselisqysdeeeiqhvveviq
nstakvivvfssgpdleplikeivrrnitgkiwlaseawasssliampqyfhvvggtigf
alkagqipgfreflkkvhprksvhngfakefweetfnchlqefrplctgdenissvetpy
idythlrisynvylavysiahalqdiytclpgrglftngscadikkveawqvlkhlrhln
ftnnmgeqvtfdecgdlvgnysiinwhlspedgsivfkevgyynvyakkgerlfineeki
lwsgfsrevpfsncsrdclagtrkgiiegeptccfecvecpdgeysdetdasacnkcpdd
fwsnenhtsciakeieflswtepfgialtlfavlgifltafvlgvfikfelsylllfsll
ccfssslffigepqdwtcrlrqpafgisfvlciscilvktnrqfllvflctfmqivicvi
wlytappssyrnqeledeiifitchegslmalgfligytcllaaicfffafksrklpenf
neakfitfsmliffivwisfipayastygkfvsaveviailaasfgllaciffnkiyi

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7dtwB (B:)
mktiialsyifclvfadykddddenlyfqgygpdqraqkkgdiilgglfpihfgvaakdq
dlksrpesvecirynfrgfrwlqamifaieeinsspallpnltlgyrifdtcntvskale
atlsfvaqnkidslnldefcncsehipstiavvgatgsgvstavanllglfyipqvsyas
ssrllsnknqfksflrtipndehqatamadiieyfrwnwvgtiaadddygrpgiekfree
aeerdicidfselisqysdeeeiqhvveviqnstakvivvfssgpdleplikeivrrnit
gkiwlaseawasssliampqyfhvvggtigfalkagqipgfreflkkvhprksvhngfak
efweetfnchlqegakgplpvdtflrgheesgdrfsnsstafrplctgdenissvetpyi
dythlrisynvylavysiahalqdiytclpgrglftngscadikkveawqvlkhlrhlnf
tnnmgeqvtfdecgdlvgnysiinwhlspedgsivfkevgyynvyakkgerlfineekil
wsgfsrevpfsncsrdclagtrkgiiegeptccfecvecpdgeysdetdasacnkcpddf
wsnenhtsciakeieflswtepfgialtlfavlgifltafvlgvfikfrntpivkatnre
lsylllfsllccfssslffigepqdwtcrlrqpafgisfvlciscilvktnrvllvfeak
iptsfhrkwwglnlqfllvflctfmqivicviwlytappssyrnqeledeiifitchegs
lmalgfligytcllaaicfffafksrklpenfneakfitfsmliffivwisfipayasty
gkfvsaveviailaasfgllaciffnkiyiilfkpsrntieevrcstaahafkvaaratl
rrsnvsrkrssslggstgstpsssissksnsedpfpqperqkqqqplaltqqeqqqqplt
lpqqqrsqqqprckqkvifgsgtvtfslsfdepqknamahrnsthqnsleaqkssdtltr
hepllplqcgetdldltvqetglqgpvggdqrpevedpeelspalvvsssqsfvisgggs
tvtenvvnshhhhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >7dtwB (B:)
gpdqraqkkgdiilgglfpihfgvaakdqdlksrpesvecirynfrgfrwlqamifaiee
insspallpnltlgyrifdtcntvskaleatlsfvaqnkidslnldefcncsehipstia
vvgatgsgvstavanllglfyipqvsyasssrllsnknqfksflrtipndehqatamadi
ieyfrwnwvgtiaadddygrpgiekfreeaeerdicidfselisqysdeeeiqhvveviq
nstakvivvfssgpdleplikeivrrnitgkiwlaseawasssliampqyfhvvggtigf
alkagqipgfreflkkvhprksvhngfakefweetfnchlqefrplctgdenissvetpy
idythlrisynvylavysiahalqdiytclpgrglftngscadikkveawqvlkhlrhln
ftnnmgeqvtfdecgdlvgnysiinwhlspedgsivfkevgyynvyakkgerlfineeki
lwsgfsrevpfsncsrdclagtrkgiiegeptccfecvecpdgeysdetdasacnkcpdd
fwsnenhtsciakeieflswtepfgialtlfavlgifltafvlgvfikfelsylllfsll
ccfssslffigepqdwtcrlrqpafgisfvlciscilvktnrqfllvflctfmqivicvi
wlytappssyrnqeledeiifitchegslmalgfligytcllaaicfffafksrklpenf
neakfitfsmliffivwisfipayastygkfvsaveviailaasfgllaciffnkiyi