PDB entry 7dra

View 7dra on RCSB PDB site
Description: Crystal structure of MERS-CoV 3CL protease (C148A) in spacegroup P212121,pH 9.0
Class: viral protein
Keywords: MERS-CoV, 3CL protease, VIRAL PROTEIN
Deposited on 2020-12-27, released 2021-12-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-12-29, with a file datestamp of 2021-12-24.
Experiment type: XRAY
Resolution: 2.78 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C-like proteinase
    Species: Middle East respiratory syndrome-related coronavirus [TaxId:1335626]
    Database cross-references and differences (RAF-indexed):
    • Uniprot T2B9I2 (0-305)
      • engineered mutation (147)
    Domains in SCOPe 2.08: d7draa_
  • Chain 'B':
    Compound: 3C-like proteinase
    Species: Middle East respiratory syndrome-related coronavirus [TaxId:1335626]
    Database cross-references and differences (RAF-indexed):
    • Uniprot T2B9I2 (0-305)
      • engineered mutation (147)
    Domains in SCOPe 2.08: d7drab_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7draA (A:)
sglvkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcpadqlsdpnydallis
mtnhsfsvqkhigapanlrvvghamqgtllkltvdvanpstpaytfttvkpgaafsvlac
yngrptgtftvvmrpnytikgsflcgsagsvgytkegsvinfcymhqmelangthtgsaf
dgtmygafmdkqvhqvqltdkycsvnvvawlyaailngcawfvkpnrtsvvsfnewalan
qftefvgtqsvdmlavktgvaieqllyaiqqlytgfqgkqilgstmledeftpedvnmqi
mgvvmq

    Sequence, based on observed residues (ATOM records): (download) 
    >7draA (A:)
lvkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcydallismtnhsfsvqkh
inlrvvghamqgtllkltvdvanpstpaytfttvkpgaafsvlacyngrptgtftvvmrp
nytikgsflcgsagsvgytkegsvinfcymhqmelangthtgsafdgtmygafmdqltdk
ycsvnvvawlyaailngcawfvkpnrtsvvsfnewalanqftefvgtqsvdmlavktgva
ieqllyaiqqlytgfqgkqilgstmledeftpedvnmqi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7draB (B:)
sglvkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcpadqlsdpnydallis
mtnhsfsvqkhigapanlrvvghamqgtllkltvdvanpstpaytfttvkpgaafsvlac
yngrptgtftvvmrpnytikgsflcgsagsvgytkegsvinfcymhqmelangthtgsaf
dgtmygafmdkqvhqvqltdkycsvnvvawlyaailngcawfvkpnrtsvvsfnewalan
qftefvgtqsvdmlavktgvaieqllyaiqqlytgfqgkqilgstmledeftpedvnmqi
mgvvmq

    Sequence, based on observed residues (ATOM records): (download) 
    >7draB (B:)
vkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcpadpnydallismtnhsfs
vqkhigapanlrvvghamqgtllkltvdvanpstpaytfttvkpgaafsvlacyngrptg
tftvvmrpnytikgsflcgsagsvgytkegsvinfcymhqmelgthtgsafdgtmygafm
dkqltdkycsvnvvawlyaailngcawfvkpnrtsvvsfnewalanqftefvgtqsvdml
avktgvaieqllyaiqqlytgfqgkqilgstmledeftpedvnmqi