PDB entry 7dq5

View 7dq5 on RCSB PDB site
Description: Crystal structure of HitB in complex with (S)-beta-phenylalanine sulfamoyladenosine
Class: ligase
Keywords: Hitachimycin, Polyketide biosynthesis, ATP binding, Adenylation, LIGASE
Deposited on 2020-12-22, released 2021-03-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-31, with a file datestamp of 2021-03-26.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Putative ATP-dependent b-aminoacyl-ACP synthetase
    Species: Embleya scabrispora [TaxId:159449]
    Gene: hitB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7dq5a_
  • Chain 'B':
    Compound: Putative ATP-dependent b-aminoacyl-ACP synthetase
    Species: Embleya scabrispora [TaxId:159449]
    Gene: hitB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7dq5b_
  • Heterogens: 8PZ, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7dq5A (A:)
mnhkvhhhhhhiegrhmrvisngrraararesvdnlywfmlaaansapdtpafvtrdgeg
gvrtlsyrelrtrvddfaaalaelgldvddrvvleanvtpdavamllacsllglpfipvs
petpsgrlrsildtaepalfaqaedggradvpatvgtarfgagglrveraprarvrhrre
ivgtdtayiiftsgttgrpkgvvmshrsvvslyraileqglitpedriattsplqfdfal
fdiglalgtgaalvpvpreelnwprrflaflgdtgatqvhgvpsiwrpvlrhepellagl
drvrgilftgedfplpelrhlqgllpharivngygatesmacsftevprpipsdlerlsi
gfplpgfdvslldehgrpveeigvagqihlrapsmfsgywddpeatarvlvsdpldprsg
rtvlrsgdlayrgedgelyfagrvdaqvqirgnrvepgeverrllefpgisaavallvpr
pgndpvlhafvvvepggadfdkakarafcadtlpgymipanivavddipltvngkvdrad
latrvagpf

    Sequence, based on observed residues (ATOM records): (download) 
    >7dq5A (A:)
raararesvdnlywfmlaaansapdtpafvtrgvrtlsyrelrtrvddfaaalaelgldv
ddrvvleanvtpdavamllacsllglpfipvspetpsgrlrsildtaepalfaqaedggr
advpatvgtarfgagglrveraprarvrhrreivgtdtayiiftpkgvvmshrsvvslyr
aileqglitpedriattsplqfdfalfdiglalgtgaalvpvpreelnwprrflaflgdt
gatqvhgvpsiwrpvlrhepellagldrvrgilftgedfplpelrhlqgllpharivngy
gatesmacsftevprpipsdlerlsigfplpgfdvslldehgrpveeigvagqihlraps
mfsgywddpeatarvlvsdpldprsgrtvlrsgdlayrgedgelyfagrvdanrvepgev
errllefpgisaavallpvlhafvvvdkakarafcadtlpgymipanivavddipltvng
kvdradlatr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7dq5B (B:)
mnhkvhhhhhhiegrhmrvisngrraararesvdnlywfmlaaansapdtpafvtrdgeg
gvrtlsyrelrtrvddfaaalaelgldvddrvvleanvtpdavamllacsllglpfipvs
petpsgrlrsildtaepalfaqaedggradvpatvgtarfgagglrveraprarvrhrre
ivgtdtayiiftsgttgrpkgvvmshrsvvslyraileqglitpedriattsplqfdfal
fdiglalgtgaalvpvpreelnwprrflaflgdtgatqvhgvpsiwrpvlrhepellagl
drvrgilftgedfplpelrhlqgllpharivngygatesmacsftevprpipsdlerlsi
gfplpgfdvslldehgrpveeigvagqihlrapsmfsgywddpeatarvlvsdpldprsg
rtvlrsgdlayrgedgelyfagrvdaqvqirgnrvepgeverrllefpgisaavallvpr
pgndpvlhafvvvepggadfdkakarafcadtlpgymipanivavddipltvngkvdrad
latrvagpf

    Sequence, based on observed residues (ATOM records): (download) 
    >7dq5B (B:)
raararesvdnlywfmlaaansapdtpafvtrvrtlsyrelrtrvddfaaalaelgldvd
drvvleanvtpdavamllacsllglpfipvspetpsgrlrsildtaepalfaqaedggra
dvpatvgtarfgagglrveraprarvrhrreivgtdtayiiftsgttgrpkgvvmshrsv
vslyraileqglitpedriattsplqfdfalfdiglalgtgaalvpvpreelnwprrfla
flgdtgatqvhgvpsiwrpvlrhepellagldrvrgilftgedfplpelrhlqgllphar
ivngygatesmacsftevprpipsdlerlsigfplpgfdvslldehgrpveeigvagqih
lrapsmfsgywddpeatarvlvsdpldprsgrtvlrsgdlayrgedgelyfagrvdaval
lhafipltvngkvdradlatr