PDB entry 7dn4

View 7dn4 on RCSB PDB site
Description: The crystal structure of Cpd8 in complex with BPTF bromodomain
Class: protein binding
Keywords: inhibitor, BPTF, bromodomain, reader, PROTEIN BINDING
Deposited on 2020-12-08, released 2021-10-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 2.84 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nucleosome-remodeling factor subunit BPTF
    Species: Homo sapiens [TaxId:9606]
    Gene: BPTF, FAC1, FALZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12830 (2-122)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7dn4a_
  • Chain 'B':
    Compound: Nucleosome-remodeling factor subunit BPTF
    Species: Homo sapiens [TaxId:9606]
    Gene: BPTF, FAC1, FALZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12830 (2-122)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7dn4b_
  • Chain 'C':
    Compound: Nucleosome-remodeling factor subunit BPTF
    Species: Homo sapiens [TaxId:9606]
    Gene: BPTF, FAC1, FALZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12830 (2-122)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7dn4c_
  • Chain 'D':
    Compound: Nucleosome-remodeling factor subunit BPTF
    Species: Homo sapiens [TaxId:9606]
    Gene: BPTF, FAC1, FALZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12830 (2-122)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7dn4d_
  • Chain 'E':
    Compound: Nucleosome-remodeling factor subunit BPTF
    Species: Homo sapiens [TaxId:9606]
    Gene: BPTF, FAC1, FALZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12830 (2-122)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7dn4e_
  • Chain 'F':
    Compound: Nucleosome-remodeling factor subunit BPTF
    Species: Homo sapiens [TaxId:9606]
    Gene: BPTF, FAC1, FALZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12830 (2-122)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7dn4f_
  • Heterogens: JC3

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7dn4A (A:)
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    Sequence, based on observed residues (ATOM records): (download) 
    >7dn4A (A:)
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  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7dn4B (B:)
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    Sequence, based on observed residues (ATOM records): (download) 
    >7dn4B (B:)
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  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7dn4C (C:)
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    Sequence, based on observed residues (ATOM records): (download) 
    >7dn4C (C:)
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  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7dn4D (D:)
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    Sequence, based on observed residues (ATOM records): (download) 
    >7dn4D (D:)
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  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7dn4E (E:)
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    Sequence, based on observed residues (ATOM records): (download) 
    >7dn4E (E:)
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  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >7dn4F (F:)
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    Sequence, based on observed residues (ATOM records): (download) 
    >7dn4F (F:)
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