PDB entry 7dli

View 7dli on RCSB PDB site
Description: Crystal structure of mouse CRY1 in complex with KL001 compound
Class: circadian clock protein
Keywords: CRY, CRY1, cryptochrome, PHR, CIRCADIAN CLOCK PROTEIN
Deposited on 2020-11-27, released 2021-06-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cryptochrome-1
    Species: Mus musculus [TaxId:10090]
    Gene: CRY1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P97784 (2-497)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7dlia1, d7dlia2
  • Chain 'B':
    Compound: Cryptochrome-1
    Species: Mus musculus [TaxId:10090]
    Gene: CRY1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P97784 (2-497)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7dlib1, d7dlib2
  • Chain 'C':
    Compound: Cryptochrome-1
    Species: Mus musculus [TaxId:10090]
    Gene: CRY1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P97784 (2-497)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7dlic1, d7dlic2
  • Heterogens: H8X, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7dliA (A:)
gtmgvnavhwfrkglrlhdnpalkeciqgadtircvyildpwfagssnvginrwrfllqc
ledldanlrklnsrlfvirgqpadvfprlfkewnitklsieydsepfgkerdaaikklat
eagvevivrishtlydldkiielnggqppltykrfqtlvskmeplempadtitsdvigkc
mtplsddhdekygvpsleelgfdtdglssavwpggetealtrlerhlerkawvanferpr
mnansllasptglspylrfgclscrlfyfkltdlykkvkknsspplslygqllwreffyt
aatnnprfdkmegnpicvqipwdknpealakwaegrtgfpwidaimtqlrqegwihhlar
havacfltrgdlwisweegmkvfeellldadwsinagswmwlscssffqqffhcycpvgf
grrtdpngdyirrylpvlrgfpakyiydpwnapegiqkvakcligvnypkpmvnhaeasr
lniermkqiyqqlsryrg

    Sequence, based on observed residues (ATOM records): (download) 
    >7dliA (A:)
vnavhwfrkglrlhdnpalkeciqgadtircvyilvginrwrfllqcledldanlrklns
rlfvirgqpadvfprlfkewnitklsieydsepfgkerdaaikklateagvevivrisht
lydldkiielnggqppltykrfqtlvskmeplempadtitsdvigkcmtplsddhdekyg
vpsleelgfdtdglssavwpggetealtrlerhlerkawvanferprmnansllasptgl
spylrfgclscrlfyfkltdlykkvkknsspplslygqllwreffytaatnnprfdkmeg
npicvqipwdknpealakwaegrtgfpwidaimtqlrqegwihhlarhavacfltrgdlw
isweegmkvfeellldadwsinagswmwlscssffcycpvgfgrrtdpngdyirrylpvl
rgfpakyiydpwnapegiqkvakcligvnypkpmvnhaeasrlniermkqiy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7dliB (B:)
gtmgvnavhwfrkglrlhdnpalkeciqgadtircvyildpwfagssnvginrwrfllqc
ledldanlrklnsrlfvirgqpadvfprlfkewnitklsieydsepfgkerdaaikklat
eagvevivrishtlydldkiielnggqppltykrfqtlvskmeplempadtitsdvigkc
mtplsddhdekygvpsleelgfdtdglssavwpggetealtrlerhlerkawvanferpr
mnansllasptglspylrfgclscrlfyfkltdlykkvkknsspplslygqllwreffyt
aatnnprfdkmegnpicvqipwdknpealakwaegrtgfpwidaimtqlrqegwihhlar
havacfltrgdlwisweegmkvfeellldadwsinagswmwlscssffqqffhcycpvgf
grrtdpngdyirrylpvlrgfpakyiydpwnapegiqkvakcligvnypkpmvnhaeasr
lniermkqiyqqlsryrg

    Sequence, based on observed residues (ATOM records): (download) 
    >7dliB (B:)
vnavhwfrkglrlhdnpalkeciqgadtircvyildpvginrwrfllqcledldanlrkl
nsrlfvirgqpadvfprlfkewnitklsieydsepfgkerdaaikklateagvevivris
htlydldkiielnggqppltykrfqtlvskmeplempadtitsdvigkcmtplsddhdek
ygvpsleelgfdtdglssavwpggetealtrlerhlerkawvanferprmnansllaspt
glspylrfgclscrlfyfkltdlykkvkknsspplslygqllwreffytaatnnprfdkm
egnpicvqipwdknpealakwaegrtgfpwidaimtqlrqegwihhlarhavacfltrgd
lwisweegmkvfeellldadwsinagswmwlscsshcycpvgfgrrtdpngdyirrylpv
lrgfpakyiydpwnapegiqkvakcligvnypkpmvnhaeasrlniermkqiyqq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7dliC (C:)
gtmgvnavhwfrkglrlhdnpalkeciqgadtircvyildpwfagssnvginrwrfllqc
ledldanlrklnsrlfvirgqpadvfprlfkewnitklsieydsepfgkerdaaikklat
eagvevivrishtlydldkiielnggqppltykrfqtlvskmeplempadtitsdvigkc
mtplsddhdekygvpsleelgfdtdglssavwpggetealtrlerhlerkawvanferpr
mnansllasptglspylrfgclscrlfyfkltdlykkvkknsspplslygqllwreffyt
aatnnprfdkmegnpicvqipwdknpealakwaegrtgfpwidaimtqlrqegwihhlar
havacfltrgdlwisweegmkvfeellldadwsinagswmwlscssffqqffhcycpvgf
grrtdpngdyirrylpvlrgfpakyiydpwnapegiqkvakcligvnypkpmvnhaeasr
lniermkqiyqqlsryrg

    Sequence, based on observed residues (ATOM records): (download) 
    >7dliC (C:)
gvnavhwfrkglrlhdnpalkeciqgadtircvyildpwfagssnvginrwrfllqcled
ldanlrklnsrlfvirgqpadvfprlfkewnitklsieydsepfgkerdaaikklateag
vevivrishtlydldkiielnggqppltykrfqtlvskmeplempadtitsdvigkcmtp
lsddhdekygvpsleelgfdtdglssavwpggetealtrlerhlerkawglspylrfgcl
scrlfyfkltdlykkvkknsspplslygqllwreffytaatnnprfdkmegnpicvqipw
dknpealakwaegrtgfpwidaimtqlrqegwihhlarhavacfltrgdlwisweegmkv
feellldadwsinagswmwlscssffqqffhcycpvgfgrrtdpngdyirrylpvlrgfp
akyiydpwnapegiqkvakcligvnypkpmvnhaeasrlniermkqiyqqlsryrg