PDB entry 7dhl

View 7dhl on RCSB PDB site
Description: Crystal structure of FGFR3 in complex with pyrimidine derivative
Class: transferase
Keywords: protein kinase, SIGNALING PROTEIN, TRANSFERASE
Deposited on 2020-11-16, released 2021-02-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-03, with a file datestamp of 2021-01-29.
Experiment type: XRAY
Resolution: 2.57 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fibroblast growth factor receptor 3
    Species: Homo sapiens [TaxId:9606]
    Gene: FGFR3, JTK4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22607 (25-End)
      • expression tag (13-24)
    Domains in SCOPe 2.08: d7dhla1, d7dhla2
  • Heterogens: H6X, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7dhlA (A:)
gshmlagvseyelpedpkwefprdkltlgkplgegcfgqvvmaeaigidkdraakpvtva
vkmlkddatdkdlsdlvsememmkmigkhkniinllgactqggplyvlveyaakgnlref
lrarrppgldysfdtckppeeqltfkdlvscayqvargmeylasqkcihrdlaarnvlvt
ednvmkiadfglardvhnldyykkttngrlpvkwmapealfdrvythqsdvwsfgvllwe
iftlggspypgipveelfkllkeghrmdkpancthdlymimrecwhaapsqrptfkqlve
dldrvltvtstde

    Sequence, based on observed residues (ATOM records): (download) 
    >7dhlA (A:)
pedpkwefprdkltlgkplgegcfgqvvmaeaigidkdraakpvtvavkmlkddatdkdl
sdlvsememmkmigkhkniinllgactqggplyvlveyaakgnlreflrarrppgldysf
eqltfkdlvscayqvargmeylasqkcihrdlaarnvlvtednvmkiadfglardvhnld
yykkttngrlpvkwmapealfdrvythqsdvwsfgvllweiftlggspypgipveelfkl
lkeghrmdkpancthdlymimrecwhaapsqrptfkqlvedldrvltvt