PDB entry 7dhc

View 7dhc on RCSB PDB site
Description: The co-crystal structure of DYRK2 with a small molecule inhibitor 10
Class: cell cycle
Keywords: kinase, inhibitor, CELL CYCLE
Deposited on 2020-11-13, released 2021-11-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-11-17, with a file datestamp of 2021-11-12.
Experiment type: XRAY
Resolution: 2.59 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity tyrosine-phosphorylation-regulated kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: DYRK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7dhca_
  • Heterogens: H99, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7dhcA (A:)
hdhvayryevlkvigkgsfgqvvkaydhkvhqhvalkmvrnekrfhrqaaeeirilehlr
kqdkdntmnvihmlenftfrnhicmtfellsmnlyelikknkfqgfslplvrkfahsilq
cldalhknriihcdlkpenillkqqgrsgikvidfgsscyehqrvytyiqsrfyrapevi
lgarygmpidmwslgcilaelltgypllpgedegdqlacmiellgmpsqklldaskrakn
fvsskgypryctvttlsdgsvvlnggrsrrgklrgppesrewgnalkgcddplfldflkq
clewdpavrmtpgqalrhpwlrrr