PDB entry 7df6

View 7df6 on RCSB PDB site
Description: Mouse Galectin-3 CRD in complex with novel tetrahydropyran-based thiodisaccharide mimic inhibitor
Class: carbohydrate
Keywords: Galectin-3 Carbohydrate Recognition Domain, Inhibitor, Complex, Tetrahydropyran, Thiodigalactoside, CARBOHYDRATE
Deposited on 2020-11-06, released 2021-06-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-23, with a file datestamp of 2021-06-18.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Galectin-3
    Species: Mus musculus [TaxId:10090]
    Gene: Lgals3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7df6a_
  • Chain 'B':
    Compound: Galectin-3
    Species: Mus musculus [TaxId:10090]
    Gene: Lgals3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7df6b_
  • Heterogens: H5O, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7df6A (A:)
mgsshhhhhhssgetvrfqghmgvpagpltvpydlplpggvmprmlitimgtvkpnanri
vldfrrgndvafhfnprfnennrrvivcntkqdnnwgkeerqsafpfesgkpfkiqvlve
adhfkvavndahllqynhrmknlreisqlgisgditltsanhami

    Sequence, based on observed residues (ATOM records): (download) 
    >7df6A (A:)
gpltvpydlplpggvmprmlitimgtvkpnanrivldfrrgndvafhfnprfnennrrvi
vcntkqdnnwgkeerqsafpfesgkpfkiqvlveadhfkvavndahllqynhrmknlrei
sqlgisgditltsanhami

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7df6B (B:)
mgsshhhhhhssgetvrfqghmgvpagpltvpydlplpggvmprmlitimgtvkpnanri
vldfrrgndvafhfnprfnennrrvivcntkqdnnwgkeerqsafpfesgkpfkiqvlve
adhfkvavndahllqynhrmknlreisqlgisgditltsanhami

    Sequence, based on observed residues (ATOM records): (download) 
    >7df6B (B:)
gpltvpydlplpggvmprmlitimgtvkpnanrivldfrrgndvafhfnprfnennrrvi
vcntkqdnnwgkeerqsafpfesgkpfkiqvlveadhfkvavndahllqynhrmknlrei
sqlgisgditltsanhami