PDB entry 7ddi

View 7ddi on RCSB PDB site
Description: crystal structures of na+,k+-atpase in complex with digitoxin
Deposited on 2020-10-29, released 2021-01-27
The last revision was dated 2021-01-27, with a file datestamp of 2021-01-22.
Experiment type: XRAY
Resolution: 3.72 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sodium/potassium-transporting ATPase subunit alpha-1
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Sodium/potassium-transporting ATPase subunit beta-1
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Sodium/potassium-transporting ATPase subunit alpha-1
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Sodium/potassium-transporting ATPase subunit beta-1
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: FXYD domain-containing ion transport regulator
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: FXYD domain-containing ion transport regulator
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: F9R, MG, NA, PCW, CLR, NAG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7ddiA (A:)
grdkyepaavsehgdkkkakkerdmdelkkevsmddhklsldelhrkygtdlsrgltpar
aaeilardgpnaltpppttpewvkfcrqlfggfsmllwigailcflaygiqaateeepqn
dnlylgvvlsavviitgcfsyyqeaksskimesfknmvpqqalvirngekmsinaeevvv
gdlvevkggdripadlriisangckvdnssltgesepqtrspdftnenpletrniaffst
ncvegtargivvytgdrtvmgriatlasgleggqtpiaaeiehfihiitgvavflgvsff
ilslileytwleavifligiivanvpegllatvtvcltltakrmarknclvknleavetl
gststicsdktgtltqnrmtvahmwsdnqiheadttenqsgvsfdktsatwlalsriagl
cnravfqanqenlpilkravagdasesallkcielccgsvkemrerytkiveipfnstnk
yqlsihknpntaeprhllvmkgaperildrcssilihgkeqpldeelkdafqnaylelgg
lgervlgfchlflpdeqfpegfqfdtddvnfpldnlcfvglismidppraavpdavgkcr
sagikvimvtgdhpitakaiakgvgiisegnetvediaarlnipvsqvnprdakacvvhg
sdlkdmtseqlddilkyhteivfartspqqkliivegcqrqgaivavtgdgvndspaskk
adigvamgiagsdvskqaadmillddnfasivtgveegrlifdnlkksiaytltsnipei
tpflifiianiplplgtvtilcidlgtdmvpaislayeqaesdimkrqprnpktdklvne
qlismaygqigmiqalggfftyfvilaengflpihllglrvnwddrwindvedsygqqwt
yeqrkiveftchtpffvtivvvqwadlvicktrrnsvfqqgmknkilifglfeetalaaf
lsycpgmgvalrmyplkptwwfcafpysllifvydevrkliirrrpggwveketyy

    Sequence, based on observed residues (ATOM records):
    >7ddiA (A:)
kerdmdelkkevsmddhklsldelhrkygtdlsrgltparaaeilardgpnaltpppttp
ewvkfcrqlfggfsmllwigailcflaygiqaateeepqndnlylgvvlsavviitgcfs
yyqeaksskimesfknmvpqqalvirngekmsinaeevvvgdlvevkggdripadlriis
angckvdnssltgesepqtrspdftnenpletrniaffstncvegtargivvytgdrtvm
griatlasgleggqtpiaaeiehfihiitgvavflgvsffilslileytwleavifligi
ivanvpegllatvtvcltltakrmarknclvknleavetlgststicsdktgtltqnrmt
vahmwsdnqiheadttenqsgvsfdktsatwlalsriaglcnravfqanqenlpilkrav
agdasesallkcielccgsvkemrerytkiveipfnstnkyqlsihknpntaeprhllvm
kgaperildrcssilihgkeqpldeelkdafqnaylelgglgervlgfchlflpdeqfpe
gfqfdtddvnfpldnlcfvglismidppraavpdavgkcrsagikvimvtgdhpitakai
akgvgiisegnetvediaarlnipvsqvnprdakacvvhgsdlkdmtseqlddilkyhte
ivfartspqqkliivegcqrqgaivavtgdgvndspaskkadigvamgiagsdvskqaad
millddnfasivtgveegrlifdnlkksiaytltsnipeitpflifiianiplplgtvti
lcidlgtdmvpaislayeqaesdimkrqprnpktdklvneqlismaygqigmiqalggff
tyfvilaengflpihllglrvnwddrwindvedsygqqwtyeqrkiveftchtpffvtiv
vvqwadlvicktrrnsvfqqgmknkilifglfeetalaaflsycpgmgvalrmyplkptw
wfcafpysllifvydevrkliirrrpggwveketyy

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7ddiB (B:)
margkakeegswkkfiwnsekkeflgrtggswfkillfyvifygclagifigtiqvmllt
isefkptyqdrvappgltqipqsqkteisfrpndpqsyesyvvsivrflekykdlaqkdd
mifedcgnvpselkergeynnergerkvcrfrlewlgncsglndetygykdgkpcviikl
nrvlgfkpkppknesletypvmkynpyvlpvhctgkrdedkekvgtmeyfglggypgfpl
qyypyygkllqpkylqplmavqftnltmdteirieckaygenigysekdrfqgrfdvkie
vks

    Sequence, based on observed residues (ATOM records):
    >7ddiB (B:)
kkfiwnsekkeflgrtggswfkillfyvifygclagifigtiqvmlltisefkptyqdrv
appgltqipqsqkteisfrpndpqsyesyvvsivrflekykdlaqkddmifedcgnvpse
lkergeynnergerkvcrfrlewlgncsglndetygykdgkpcviiklnrvlgfkpkppk
nesletypvmkynpyvlpvhctgkrdedkekvgtmeyfglggypgfplqyypyygkllqp
kylqplmavqftnltmdteirieckaygenigysekdrfqgrfdvkievks

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7ddiC (C:)
grdkyepaavsehgdkkkakkerdmdelkkevsmddhklsldelhrkygtdlsrgltpar
aaeilardgpnaltpppttpewvkfcrqlfggfsmllwigailcflaygiqaateeepqn
dnlylgvvlsavviitgcfsyyqeaksskimesfknmvpqqalvirngekmsinaeevvv
gdlvevkggdripadlriisangckvdnssltgesepqtrspdftnenpletrniaffst
ncvegtargivvytgdrtvmgriatlasgleggqtpiaaeiehfihiitgvavflgvsff
ilslileytwleavifligiivanvpegllatvtvcltltakrmarknclvknleavetl
gststicsdktgtltqnrmtvahmwsdnqiheadttenqsgvsfdktsatwlalsriagl
cnravfqanqenlpilkravagdasesallkcielccgsvkemrerytkiveipfnstnk
yqlsihknpntaeprhllvmkgaperildrcssilihgkeqpldeelkdafqnaylelgg
lgervlgfchlflpdeqfpegfqfdtddvnfpldnlcfvglismidppraavpdavgkcr
sagikvimvtgdhpitakaiakgvgiisegnetvediaarlnipvsqvnprdakacvvhg
sdlkdmtseqlddilkyhteivfartspqqkliivegcqrqgaivavtgdgvndspaskk
adigvamgiagsdvskqaadmillddnfasivtgveegrlifdnlkksiaytltsnipei
tpflifiianiplplgtvtilcidlgtdmvpaislayeqaesdimkrqprnpktdklvne
qlismaygqigmiqalggfftyfvilaengflpihllglrvnwddrwindvedsygqqwt
yeqrkiveftchtpffvtivvvqwadlvicktrrnsvfqqgmknkilifglfeetalaaf
lsycpgmgvalrmyplkptwwfcafpysllifvydevrkliirrrpggwveketyy

    Sequence, based on observed residues (ATOM records):
    >7ddiC (C:)
kerdmdelkkevsmddhklsldelhrkygtdlsrgltparaaeilardgpnaltpppttp
ewvkfcrqlfggfsmllwigailcflaygiqaateeepqndnlylgvvlsavviitgcfs
yyqeaksskimesfknmvpqqalvirngekmsinaeevvvgdlvevkggdripadlriis
angckvdnssltgesepqtrspdftnenpletrniaffstncvegtargivvytgdrtvm
griatlasgleggqtpiaaeiehfihiitgvavflgvsffilslileytwleavifligi
ivanvpegllatvtvcltltakrmarknclvknleavetlgststicsdktgtltqnrmt
vahmwsdnqiheadttenqsgvsfdktsatwlalsriaglcnravfqanqenlpilkrav
agdasesallkcielccgsvkemrerytkiveipfnstnkyqlsihknpntaeprhllvm
kgaperildrcssilihgkeqpldeelkdafqnaylelgglgervlgfchlflpdeqfpe
gfqfdtddvnfpldnlcfvglismidppraavpdavgkcrsagikvimvtgdhpitakai
akgvgiisegnetvediaarlnipvsqvnprdakacvvhgsdlkdmtseqlddilkyhte
ivfartspqqkliivegcqrqgaivavtgdgvndspaskkadigvamgiagsdvskqaad
millddnfasivtgveegrlifdnlkksiaytltsnipeitpflifiianiplplgtvti
lcidlgtdmvpaislayeqaesdimkrqprnpktdklvneqlismaygqigmiqalggff
tyfvilaengflpihllglrvnwddrwindvedsygqqwtyeqrkiveftchtpffvtiv
vvqwadlvicktrrnsvfqqgmknkilifglfeetalaaflsycpgmgvalrmyplkptw
wfcafpysllifvydevrkliirrrpggwveketyy

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7ddiD (D:)
margkakeegswkkfiwnsekkeflgrtggswfkillfyvifygclagifigtiqvmllt
isefkptyqdrvappgltqipqsqkteisfrpndpqsyesyvvsivrflekykdlaqkdd
mifedcgnvpselkergeynnergerkvcrfrlewlgncsglndetygykdgkpcviikl
nrvlgfkpkppknesletypvmkynpyvlpvhctgkrdedkekvgtmeyfglggypgfpl
qyypyygkllqpkylqplmavqftnltmdteirieckaygenigysekdrfqgrfdvkie
vks

    Sequence, based on observed residues (ATOM records):
    >7ddiD (D:)
kkfiwnsekkeflgrtggswfkillfyvifygclagifigtiqvmlltisefkptyqdrv
appgltqipqsqkteisfrpndpqsyesyvvsivrflekykdlaqkddmifedcgnvpse
lkergeynnergerkvcrfrlewlgncsggykdgkpcviiklnrvlgfkpkppkneslet
ypvmkynpyvlpvhctgkrdedkekvgtmeyfglggypgfplqyypyygkllqpkylqpl
mavqftnltmdteirieckaygenigysekdrfqgrfdvkievks

  • Chain 'E':
    Sequence, based on SEQRES records:
    >7ddiE (E:)
maglstddggspkgdvdpfyydyetvrngglifaalafivgliiilskrlrcggkkhrpi
nedel

    Sequence, based on observed residues (ATOM records):
    >7ddiE (E:)
dpfyydyetvrngglifaalafivgliiilsk

  • Chain 'G':
    Sequence, based on SEQRES records:
    >7ddiG (G:)
maglstddggspkgdvdpfyydyetvrngglifaalafivgliiilskrlrcggkkhrpi
nedel

    Sequence, based on observed residues (ATOM records):
    >7ddiG (G:)
dpfyydyetvrngglifaalafivgliiilsk