PDB entry 7dcf

View 7dcf on RCSB PDB site
Description: Crystal structure of EHMT2 SET domain in complex with compound 10
Class: transferase
Keywords: protein-small molecule inhibitor complex, transferase-transferase inhibitor complex, transferase
Deposited on 2020-10-26, released 2021-02-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-10, with a file datestamp of 2021-02-05.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase EHMT2
    Species: Homo sapiens [TaxId:9606]
    Gene: EHMT2, BAT8, C6orf30, G9A, KMT1C, NG36
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7dcfa_
  • Chain 'B':
    Compound: Histone-lysine N-methyltransferase EHMT2
    Species: Homo sapiens [TaxId:9606]
    Gene: EHMT2, BAT8, C6orf30, G9A, KMT1C, NG36
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7dcfb_
  • Heterogens: H30, ZN, SAM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7dcfA (A:)
gsnrairtekiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnith
lqhctcvddcsssnclcgqlsircwydkdgrllqefnkiepplifecnqacscwrncknr
vvqsgikvrlqlyrtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdld
nkdgevycidaryygnisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeel
gfdygdrfwdikskyftcqcgsekckhsaeaialeqsrlarld

    Sequence, based on observed residues (ATOM records): (download) 
    >7dcfA (A:)
tekiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnithlqhctcv
ddcsssnclccwydkdgrllqefnkiepplifecnqacscwrncknrvvqsgikvrlqly
rtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdldnkevycidaryyg
nisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeelgfdygdrfwdiksky
ftcqcgsekckhsaeaiale

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7dcfB (B:)
gsnrairtekiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnith
lqhctcvddcsssnclcgqlsircwydkdgrllqefnkiepplifecnqacscwrncknr
vvqsgikvrlqlyrtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdld
nkdgevycidaryygnisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeel
gfdygdrfwdikskyftcqcgsekckhsaeaialeqsrlarld

    Sequence, based on observed residues (ATOM records): (download) 
    >7dcfB (B:)
kiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnithlqhctcvdd
csssnclcgqlsircwydkrllqefnepplifecnqacscwrncknrvvqsgikvrlqly
rtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdldnkevycidaryyg
nisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeelgfdygdrfwdiksky
ftcqcgsekckhsaeaial