PDB entry 7dbj

View 7dbj on RCSB PDB site
Description: Crystal structure of human LDHB in complex with NADH, oxamate, and AXKO-0046
Class: oxidoreductase
Keywords: Lactate dehydrogenase, Inhibitor, Complex, OXIDOREDUCTASE
Deposited on 2020-10-20, released 2021-10-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-11-10, with a file datestamp of 2021-11-05.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: L-lactate dehydrogenase B chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7dbja1, d7dbja2
  • Chain 'B':
    Compound: L-lactate dehydrogenase B chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7dbjb1, d7dbjb2
  • Chain 'C':
    Compound: L-lactate dehydrogenase B chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7dbjc1, d7dbjc2
  • Chain 'D':
    Compound: L-lactate dehydrogenase B chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7dbjd1, d7dbjd2
  • Heterogens: NAI, OXM, EDO, H1U, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7dbjA (A:)
atlkekliapvaeeeatvpnnkitvvgvgqvgmacaisilgksladelalvdvledklkg
emmdlqhgslflqtpkivadkdysvtanskivvvtagvrqqegesrlnlvqrnvnvfkfi
ipqivkyspdciiivvsnpvdiltyvtwklsglpkhrvigsgcnldsarfrylmaeklgi
hpsschgwilgehgdssvavwsgvnvagvslqelnpemgtdndsenwkevhkmvvesaye
viklkgytnwaiglsvadliesmlknlsrihpvstmvkgmygienevflslpcilnargl
tsvinqklkddevaqlkksadtlwdiqkdlkdl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7dbjB (B:)
atlkekliapvaeeeatvpnnkitvvgvgqvgmacaisilgksladelalvdvledklkg
emmdlqhgslflqtpkivadkdysvtanskivvvtagvrqqegesrlnlvqrnvnvfkfi
ipqivkyspdciiivvsnpvdiltyvtwklsglpkhrvigsgcnldsarfrylmaeklgi
hpsschgwilgehgdssvavwsgvnvagvslqelnpemgtdndsenwkevhkmvvesaye
viklkgytnwaiglsvadliesmlknlsrihpvstmvkgmygienevflslpcilnargl
tsvinqklkddevaqlkksadtlwdiqkdlkdl

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7dbjC (C:)
atlkekliapvaeeeatvpnnkitvvgvgqvgmacaisilgksladelalvdvledklkg
emmdlqhgslflqtpkivadkdysvtanskivvvtagvrqqegesrlnlvqrnvnvfkfi
ipqivkyspdciiivvsnpvdiltyvtwklsglpkhrvigsgcnldsarfrylmaeklgi
hpsschgwilgehgdssvavwsgvnvagvslqelnpemgtdndsenwkevhkmvvesaye
viklkgytnwaiglsvadliesmlknlsrihpvstmvkgmygienevflslpcilnargl
tsvinqklkddevaqlkksadtlwdiqkdlkdl

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7dbjD (D:)
atlkekliapvaeeeatvpnnkitvvgvgqvgmacaisilgksladelalvdvledklkg
emmdlqhgslflqtpkivadkdysvtanskivvvtagvrqqegesrlnlvqrnvnvfkfi
ipqivkyspdciiivvsnpvdiltyvtwklsglpkhrvigsgcnldsarfrylmaeklgi
hpsschgwilgehgdssvavwsgvnvagvslqelnpemgtdndsenwkevhkmvvesaye
viklkgytnwaiglsvadliesmlknlsrihpvstmvkgmygienevflslpcilnargl
tsvinqklkddevaqlkksadtlwdiqkdlkdl