PDB entry 7cwf

View 7cwf on RCSB PDB site
Description: Crystal structure of PDE8A catalytic domain in complex with 2c
Class: hydrolase
Keywords: cAMP-specific, HYDROLASE, Selective PDE8A inhibitor
Deposited on 2020-08-28, released 2021-09-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-09-01, with a file datestamp of 2021-08-27.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE8A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cwfa_
  • Heterogens: GJR, ZN, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7cwfA (A:)
ddvppriarameneeywdfdifeleaathnrpliylglkmfarfgiceflhcsestlrsw
lqiieanyhssnpyhnsthsadvlhatayflskeriketldpidevaaliaatihdvdhp
grtnsflcnagselailyndtavleshhaalafqlttgddkcnifknmerndyrtlrqgi
idmvlatemtkhfehvnkfvnsinkplatleengetdknqevintmlrtpenrtlikrml
ikcadvsnpcrplqyciewaariseeyfsqtdeekqqglpvvmpvfdrntcsipksqisf
idyfitdmfdawdafvdlpdlmqhldnnfkywkgldem