PDB entry 7coh

View 7coh on RCSB PDB site
Description: Dimeric Form of Bovine Heart Cytochrome c Oxidase in the Fully Oxidized State
Class: oxidoreductase
Keywords: Dimer, Fully Oxidized, OXIDOREDUCTASE
Deposited on 2020-08-04, released 2021-04-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-04-07, with a file datestamp of 2021-04-02.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: N/A
AEROSPACI score: 0.67 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome c oxidase subunit 1
    Species: Bos taurus [TaxId:9913]
    Gene: MT-CO1, COI, COXI, MTCO1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7coha_
  • Chain 'B':
    Compound: Cytochrome c oxidase subunit 2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohb1, d7cohb2
  • Chain 'C':
    Compound: Cytochrome c oxidase subunit 3
    Species: Bos taurus [TaxId:9913]
    Gene: MT-CO3, COIII, COXIII, MTCO3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohc_
  • Chain 'D':
    Compound: Cytochrome c oxidase subunit 4 isoform 1
    Species: Bos taurus [TaxId:9913]
    Gene: COX4I1, COX4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohd_
  • Chain 'E':
    Compound: Cytochrome c oxidase subunit 5A
    Species: Bos taurus [TaxId:9913]
    Gene: COX5A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohe_
  • Chain 'F':
    Compound: Cytochrome c oxidase subunit 5B
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohf_
  • Chain 'G':
    Compound: Cytochrome c oxidase subunit 6A2, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Gene: COX6A2, COX6A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohg_
  • Chain 'H':
    Compound: Cytochrome c oxidase subunit 6B1
    Species: Bos taurus [TaxId:9913]
    Gene: COX6B1, COX6B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohh_
  • Chain 'I':
    Compound: Cytochrome c oxidase subunit 6C
    Species: Bos taurus [TaxId:9913]
    Gene: COX6C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohi_
  • Chain 'J':
    Compound: Cytochrome c oxidase subunit 7A1
    Species: Bos taurus [TaxId:9913]
    Gene: COX7A1, COX7A, COX7AH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohj_
  • Chain 'K':
    Compound: Cytochrome c oxidase subunit 7B
    Species: Bos taurus [TaxId:9913]
    Gene: COX7B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohk_
  • Chain 'L':
    Compound: cytochrome c oxidase subunit 7c, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Gene: COX7C, COX7CP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohl_
  • Chain 'M':
    Compound: Cytochrome c oxidase subunit 8B
    Species: Bos taurus [TaxId:9913]
    Gene: COX8B, COX8H
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohm_
  • Chain 'N':
    Compound: Cytochrome c oxidase subunit 1
    Species: Bos taurus [TaxId:9913]
    Gene: MT-CO1, COI, COXI, MTCO1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohn_
  • Chain 'O':
    Compound: Cytochrome c oxidase subunit 2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7coho1, d7coho2
  • Chain 'P':
    Compound: Cytochrome c oxidase subunit 3
    Species: Bos taurus [TaxId:9913]
    Gene: MT-CO3, COIII, COXIII, MTCO3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohp_
  • Chain 'Q':
    Compound: Cytochrome c oxidase subunit 4 isoform 1
    Species: Bos taurus [TaxId:9913]
    Gene: COX4I1, COX4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohq_
  • Chain 'R':
    Compound: Cytochrome c oxidase subunit 5A
    Species: Bos taurus [TaxId:9913]
    Gene: COX5A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohr_
  • Chain 'S':
    Compound: Cytochrome c oxidase subunit 5B
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohs_
  • Chain 'T':
    Compound: Cytochrome c oxidase subunit 6A2, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Gene: COX6A2, COX6A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7coht_
  • Chain 'U':
    Compound: Cytochrome c oxidase subunit 6B1
    Species: Bos taurus [TaxId:9913]
    Gene: COX6B1, COX6B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohu_
  • Chain 'V':
    Compound: Cytochrome c oxidase subunit 6C
    Species: Bos taurus [TaxId:9913]
    Gene: COX6C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohv_
  • Chain 'W':
    Compound: Cytochrome c oxidase subunit 7A1
    Species: Bos taurus [TaxId:9913]
    Gene: COX7A1, COX7A, COX7AH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohw_
  • Chain 'X':
    Compound: Cytochrome c oxidase subunit 7B
    Species: Bos taurus [TaxId:9913]
    Gene: COX7B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohx_
  • Chain 'Y':
    Compound: cytochrome c oxidase subunit 7c, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Gene: COX7C, COX7CP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohy_
  • Chain 'Z':
    Compound: Cytochrome c oxidase subunit 8B
    Species: Bos taurus [TaxId:9913]
    Gene: COX8B, COX8H
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cohz_
  • Heterogens: CDL, CHD, DMU, FME, LFA, PEK, PGV, HEA, CU, MG, NA, PER, EDO, CUA, UNX, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7cohA (A:)
mfinrwlfstnhkdigtlyllfgawagmvgtalslliraelgqpgtllgddqiynvvvta
hafvmiffmvmpimiggfgnwlvplmigapdmafprmnnmsfwllppsfllllassmvea
gagtgwtvypplagnlahagasvdltifslhlagvssilgainfittiinmkppamsqyq
tplfvwsvmitavllllslpvlaagitmlltdrnlnttffdpagggdpilyqhlfwffgh
pevyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwahhmftvgmdvd
trayftsatmiiaiptgvkvfswlatlhggnikwspammwalgfiflftvggltgivlan
ssldivlhdtyyvvahfhyvlsmgavfaimggfvhwfplfsgytlndtwakihfaimfvg
vnmtffpqhflglsgmprrysdypdaytmwntissmgsfisltavmlmvfiiweafaskr
evltvdltttnlewlngcpppyhtfeeptyvnlk

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohA (A:)
mfinrwlfstnhkdigtlyllfgawagmvgtalslliraelgqpgtllgddqiynvvvta
hafvmiffmvmpimiggfgnwlvplmigapdmafprmnnmsfwllppsfllllassmvea
gagtgwtvypplagnlahagasvdltifslhlagvssilgainfittiinmkppamsqyq
tplfvwsvmitavllllslpvlaagitmlltdrnlnttffdpagggdpilyqhlfwffgh
pevyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwahhmftvgmdvd
trayftsatmiiaiptgvkvfswlatlhggnikwspammwalgfiflftvggltgivlan
ssldivlhdtyyvvahfhyvlsmgavfaimggfvhwfplfsgytlndtwakihfaimfvg
vnmtffpqhflglsgmprrysdypdaytmwntissmgsfisltavmlmvfiiweafaskr
evltvdltttnlewlngcpppyhtfeeptyvnl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7cohB (B:)
maypmqlgfqdatspimeellhfhdhtlmivflisslvlyiislmlttklthtstmdaqe
vetiwtilpaiililialpslrilymmdeinnpsltvktmghqwywsyeytdyedlsfds
ymiptselkpgelrllevdnrvvlpmemtirmlvssedvlhswavpslglktdaipgrln
qttlmssrpglyygqcseicgsnhsfmpivlelvplkyfekwsasml

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7cohC (C:)
mthqthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrd
virestfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptg
ihplnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqase
yyeapftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaaw
ywhfvdvvwlflyvsiywwgs

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohC (C:)
qthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrdvir
estfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptgihp
lnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqaseyye
apftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaawywh
fvdvvwlflyvsiywwgs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7cohD (D:)
ahgsvvksedyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvely
rlkfkesfaemnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqt
krmldmkvapiqgfsakwdydknewkk

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohD (D:)
svvksedyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvelyrlk
fkesfaemnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqtkrm
ldmkvapiqgfsakwdydknewk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7cohE (E:)
shgshetdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlnd
fasavrilevvkdkagphkeiypyviqelrptlnelgistpeelgldkv

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohE (E:)
tdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlndfasavr
ilevvkdkagphkeiypyviqelrptlnelgistpeelgldk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >7cohF (F:)
asgggvptdeeqatglerevmlaarkgqdpynilapkatsgtkedpnlvpsitnkrivgc
iceednstviwfwlhkgeaqrcpscgthyklvphqlah

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohF (F:)
gggvptdeeqatglerevmlaarkgqdpynilapkatsgtkedpnlvpsitnkrivgcic
eednstviwfwlhkgeaqrcpscgthyklvp

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >7cohG (G:)
asaakgdhggtgartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpf
swgdgnhtffhnprvnplptgyekp

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohG (G:)
gartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpfswgdgnhtffh
nprvnplptgye

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >7cohH (H:)
aediqakiknyqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvy
kslcpiswvstwddrraegtfpgki

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohH (H:)
yqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvykslcpiswvs
twddrraegtfpgki

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >7cohI (I:)
stalakpqmrgllarrlrfhivgafmvslgfatfykfavaekrkkayadfyrnydsmkdf
eemrkagifqsak

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohI (I:)
alakpqmrgllarrlrfhivgafmvslgfatfykfavaekrkkayadfyrnydsmkdfee
mrkagifqsa

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >7cohJ (J:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfphkk

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohJ (J:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfp

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >7cohK (K:)
ihqkrapdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewreq

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohK (K:)
apdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewr

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >7cohL (L:)
shyeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllkk

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohL (L:)
yeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllk

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >7cohM (M:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldnykkssaa

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohM (M:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldny

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >7cohN (N:)
mfinrwlfstnhkdigtlyllfgawagmvgtalslliraelgqpgtllgddqiynvvvta
hafvmiffmvmpimiggfgnwlvplmigapdmafprmnnmsfwllppsfllllassmvea
gagtgwtvypplagnlahagasvdltifslhlagvssilgainfittiinmkppamsqyq
tplfvwsvmitavllllslpvlaagitmlltdrnlnttffdpagggdpilyqhlfwffgh
pevyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwahhmftvgmdvd
trayftsatmiiaiptgvkvfswlatlhggnikwspammwalgfiflftvggltgivlan
ssldivlhdtyyvvahfhyvlsmgavfaimggfvhwfplfsgytlndtwakihfaimfvg
vnmtffpqhflglsgmprrysdypdaytmwntissmgsfisltavmlmvfiiweafaskr
evltvdltttnlewlngcpppyhtfeeptyvnlk

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohN (N:)
mfinrwlfstnhkdigtlyllfgawagmvgtalslliraelgqpgtllgddqiynvvvta
hafvmiffmvmpimiggfgnwlvplmigapdmafprmnnmsfwllppsfllllassmvea
gagtgwtvypplagnlahagasvdltifslhlagvssilgainfittiinmkppamsqyq
tplfvwsvmitavllllslpvlaagitmlltdrnlnttffdpagggdpilyqhlfwffgh
pevyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwahhmftvgmdvd
trayftsatmiiaiptgvkvfswlatlhggnikwspammwalgfiflftvggltgivlan
ssldivlhdtyyvvahfhyvlsmgavfaimggfvhwfplfsgytlndtwakihfaimfvg
vnmtffpqhflglsgmprrysdypdaytmwntissmgsfisltavmlmvfiiweafaskr
evltvdltttnlewlngcpppyhtfeeptyvnl

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7cohO (O:)
maypmqlgfqdatspimeellhfhdhtlmivflisslvlyiislmlttklthtstmdaqe
vetiwtilpaiililialpslrilymmdeinnpsltvktmghqwywsyeytdyedlsfds
ymiptselkpgelrllevdnrvvlpmemtirmlvssedvlhswavpslglktdaipgrln
qttlmssrpglyygqcseicgsnhsfmpivlelvplkyfekwsasml

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >7cohP (P:)
mthqthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrd
virestfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptg
ihplnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqase
yyeapftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaaw
ywhfvdvvwlflyvsiywwgs

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohP (P:)
qthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrdvir
estfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptgihp
lnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqaseyye
apftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaawywh
fvdvvwlflyvsiywwgs

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >7cohQ (Q:)
ahgsvvksedyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvely
rlkfkesfaemnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqt
krmldmkvapiqgfsakwdydknewkk

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohQ (Q:)
dyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvelyrlkfkesfa
emnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqtkrmldmkva
piqgfsakwdydknewk

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >7cohR (R:)
shgshetdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlnd
fasavrilevvkdkagphkeiypyviqelrptlnelgistpeelgldkv

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohR (R:)
tdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlndfasavr
ilevvkdkagphkeiypyviqelrptlnelgistpeelgldk

  • Chain 'S':
    Sequence, based on SEQRES records: (download) 
    >7cohS (S:)
asgggvptdeeqatglerevmlaarkgqdpynilapkatsgtkedpnlvpsitnkrivgc
iceednstviwfwlhkgeaqrcpscgthyklvphqlah

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohS (S:)
gggvptdeeqatglerevmlaarkgqdpynilapkatsgtkedpnlvpsitnkrivgcic
eednstviwfwlhkgeaqrcpscgthyklvp

  • Chain 'T':
    Sequence, based on SEQRES records: (download) 
    >7cohT (T:)
asaakgdhggtgartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpf
swgdgnhtffhnprvnplptgyekp

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohT (T:)
gartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpfswgdgnhtffh
nprvnplptgye

  • Chain 'U':
    Sequence, based on SEQRES records: (download) 
    >7cohU (U:)
aediqakiknyqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvy
kslcpiswvstwddrraegtfpgki

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohU (U:)
yqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvykslcpiswvs
twddrraegtfpgki

  • Chain 'V':
    Sequence, based on SEQRES records: (download) 
    >7cohV (V:)
stalakpqmrgllarrlrfhivgafmvslgfatfykfavaekrkkayadfyrnydsmkdf
eemrkagifqsak

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohV (V:)
alakpqmrgllarrlrfhivgafmvslgfatfykfavaekrkkayadfyrnydsmkdfee
mrkagifqsa

  • Chain 'W':
    Sequence, based on SEQRES records: (download) 
    >7cohW (W:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfphkk

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohW (W:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfp

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >7cohX (X:)
ihqkrapdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewreq

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohX (X:)
apdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewr

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >7cohY (Y:)
shyeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllkk

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohY (Y:)
yeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllk

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >7cohZ (Z:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldnykkssaa

    Sequence, based on observed residues (ATOM records): (download) 
    >7cohZ (Z:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldny