PDB entry 7co8

View 7co8 on RCSB PDB site
Description: ternary complex of dna polymerase mu with 2-nt gapped dna (t:dgmpnpp)
Deposited on 2020-08-04, released 2021-06-30
The last revision was dated 2021-06-30, with a file datestamp of 2021-06-25.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-directed DNA/RNA polymerase mu
    Species: Homo sapiens [TaxId:9606]
    Gene: POLM, polmu
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NP87 (Start-481)
      • engineered mutation (397)
  • Chain 'D':
    Compound: DNA (5'-d(p*gp*cp*cp*g)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'P':
    Compound: DNA (5'-d(*cp*gp*tp*a)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'T':
    Compound: DNA (5'-d(*cp*gp*gp*cp*tp*tp*tp*ap*cp*g)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: XG4, K, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7co8A (A:)
mlpkrrrarvgspsgdaasstppstrfpgvaiylveprmgrsrrafltglarskgfrvld
acsseathvvmeetsaeeavswqerrmaaappgctppalldiswlteslgagqpvpvecr
hrlevagprkgplspawmpayacqrptplthhntglsealeilaeaagfegsegrlltfc
raasvlkalpspvttlsqlqglphfgehssrvvqellehgvceevervrrseryqtmklf
tqifgvgvktadrwyreglrtlddlreqpqkltqqqkaglqhhqdlstpvlrsdvdalqq
vveeavgqalpgatvtltggfrrgklqghdvdflithpkegqeagllprvmcrlqdqgli
lyhqhqhsccesptrlaqqshmdafersfcifrlpqpgswkavrvdlvvapvsqfpfall
gwtgsklfqrelrrfsrkekglwlnshglfdpeqktffqaaseedifrhlgleylppeqr
na

    Sequence, based on observed residues (ATOM records):
    >7co8A (A:)
payacqrptplthhntglsealeilaeaagfegsegrlltfcraasvlkalpspvttlsq
lqglphfgehssrvvqellehgvceevervrrseryqtmklftqifgvgvktadrwyreg
lrtlddlreqpqkltqqqkaglqhhqdlstpvlrsdvdalqqvveeavgqalpgatvtlt
ggfrrgklqghdvdflithpkegqeagllprvmcrlqdqglilyhqhqhsmdafersfci
frlpqpgswkavrvdlvvapvsqfpfallgwtgsklfqrelrrfsrkekglwlnshglfd
peqktffqaaseedifrhlgleylppeqrna

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.