PDB entry 7cnm

View 7cnm on RCSB PDB site
Description: YDX in complex with tubulin
Class: cell cycle
Keywords: YDX, tubulin, protein-drug complex, CELL CYCLE
Deposited on 2020-08-02, released 2021-08-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-08-04, with a file datestamp of 2021-07-30.
Experiment type: XRAY
Resolution: 2.44 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulin alpha-1B chain
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Tubulin beta chain
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Tubulin alpha-1B chain
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Tubulin beta chain
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Stathmin-4
    Species: Mus musculus [TaxId:10090]
    Gene: STMN4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63042 (2-142)
      • initiating methionine (0)
      • expression tag (1)
    Domains in SCOPe 2.08: d7cnme_
  • Chain 'F':
    Compound: tubulin tyrosine ligase
    Species: Gallus gallus [TaxId:9031]
    Gene: TTL
    Database cross-references and differences (RAF-indexed):
    • Uniprot E1BQ43 (0-377)
      • expression tag (378-383)
    Domains in SCOPe 2.08: d7cnmf1, d7cnmf2, d7cnmf3
  • Heterogens: G70, GTP, MG, CA, GDP, MES, ACP, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7cnmE (E:)
madmevielnkctsgqsfevilkppsfdgvpefnaslprrrdpsleeiqkkleaaeerrk
yqeaellkhlaekrehereviqkaieennnfikmakeklaqkmesnkenreahlaamler
lqekdkhaeevrknkelkeeasr

    Sequence, based on observed residues (ATOM records): (download) 
    >7cnmE (E:)
mevielnkctsgqsfevilkppsdpsleeiqkkleaaeerrkyqeaellkhlaekreher
eviqkaieennnfikmakeklaqkmesnkenreahlaamlerlqekdkhaeevrknkelk
e

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >7cnmF (F:)
mytfvvrdenssvyaevsrlllatgqwkrlrkdnprfnlmlgernrlpfgrlghepglvq
lvnyyrgadklcrkaslvkliktspelsesctwfpesyviyptnlktpvapaqngirhli
nntrtderevflaaynrrregregnvwiakssagakgegilisseaselldfideqgqvh
viqkylekplllepghrkfdirswvlvdhlyniylyregvlrtssepynsanfqdktchl
tnhciqkeysknygryeegnemffeefnqylmdalnttlensillqikhiirsclmciep
aistkhlhyqsfqlfgfdfmvdeelkvwlievngapacaqklyaelcqgivdvaissvfp
ladtgqktsqptsifiklhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7cnmF (F:)
mytfvvrdenssvyaevsrlllatgqwkrlrkdnprfnlmlgernrlpfgrlghepglvq
lvnyyrgadklcrkaslvkliktspelsesctwfpesyviyptderevflaaynrrregr
egnvwialisseaselldfideqgqvhviqkylekplllepghrkfdirswvlvdhlyni
ylyregvlrtssepynsanfqdktchltnhciqknygryeegnemffeefnqylmdalnt
tlensillqikhiirsclmciepaistkhlhyqsfqlfgfdfmvdeelkvwlievngapa
caqklyaelcqgivdvaissvfplatsifiklhhhhhh