PDB entry 7cn0

View 7cn0 on RCSB PDB site
Description: cryo-em structure of k+-bound herg channel
Deposited on 2020-07-29, released 2021-01-20
The last revision was dated 2021-03-17, with a file datestamp of 2021-03-12.
Experiment type: EM
Resolution: 3.9 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: potassium channel 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7CN0
  • Chain 'B':
    Compound: potassium channel 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7CN0
  • Chain 'C':
    Compound: potassium channel 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7CN0
  • Chain 'D':
    Compound: potassium channel 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7CN0
  • Heterogens: K

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7cn0A (A:)
mpvrrghvapqntfldtiirkfegqsrkfiianarvencaviycndgfcelcgysraevm
qrpctcdflhgprtqrraaaqiaqallgaeerkveiafyrkdgscflclvdvvpvknedg
avimfilnfevvmekdmvgssptsdreiiapkikerthnvtekvtqvlslgadvlpeykl
qaprihrwtilhyspfkavwdwlilllviytavftpysaafllketeegppatecgyacq
plavvdlivdimfivdilinfrttyvnaneevvshpgriavhyfkgwflidmvaaipfdl
lifgsgseeligllktarllrlvrvarkldryseygaavlfllmctfaliahwlaciwya
ignmeqphmdsrigwlhnlgdqigkpynssglggpsikdkyvtalyftfssltsvgfgnv
spntnsekifsicvmligslmyasifgnvsaiiqrlysgtaryhtqmlrvrefirfhqip
nplrqrleeyfqhawsytngidmnavlkgfpeclqadiclhlnrsllqhckpfrgatkgc
lralamkfktthappgdtlvhagdlltalyfisrgsieilrgdvvvailgkndifgepln
lyarpgksngdvraltycdlhkihrddllevldmypefsdhfwssleitfnlrdtnmipg
grqyqelprcpaptpsllniplsspgrrprgdvesrldalqrqlnrletrlsadmatvlq
llqrqmtlvppaysavttpgpgptstspllpvsplptltldslsqvsqfmaceelppgap
elpqegptrrlslpgqlgaltsqplhrhgsdpgslevlfq

    Sequence, based on observed residues (ATOM records):
    >7cn0A (A:)
hyspfkavwdwlilllviytavftpysaafllavvdlivdimfivdilinfrttyvnane
evvshpgriavhyfkgwflidmvaaipligllktarllrlvrvarkldrysgaavlfllm
ctfaliahwlaciwyaignmeqpigwlhnlgdqigkpggpsikdkyvtalyftfssltsv
gfgnvspntnsekifsicvmligslmyasifgnvsaiiqrl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7cn0B (B:)
mpvrrghvapqntfldtiirkfegqsrkfiianarvencaviycndgfcelcgysraevm
qrpctcdflhgprtqrraaaqiaqallgaeerkveiafyrkdgscflclvdvvpvknedg
avimfilnfevvmekdmvgssptsdreiiapkikerthnvtekvtqvlslgadvlpeykl
qaprihrwtilhyspfkavwdwlilllviytavftpysaafllketeegppatecgyacq
plavvdlivdimfivdilinfrttyvnaneevvshpgriavhyfkgwflidmvaaipfdl
lifgsgseeligllktarllrlvrvarkldryseygaavlfllmctfaliahwlaciwya
ignmeqphmdsrigwlhnlgdqigkpynssglggpsikdkyvtalyftfssltsvgfgnv
spntnsekifsicvmligslmyasifgnvsaiiqrlysgtaryhtqmlrvrefirfhqip
nplrqrleeyfqhawsytngidmnavlkgfpeclqadiclhlnrsllqhckpfrgatkgc
lralamkfktthappgdtlvhagdlltalyfisrgsieilrgdvvvailgkndifgepln
lyarpgksngdvraltycdlhkihrddllevldmypefsdhfwssleitfnlrdtnmipg
grqyqelprcpaptpsllniplsspgrrprgdvesrldalqrqlnrletrlsadmatvlq
llqrqmtlvppaysavttpgpgptstspllpvsplptltldslsqvsqfmaceelppgap
elpqegptrrlslpgqlgaltsqplhrhgsdpgslevlfq

    Sequence, based on observed residues (ATOM records):
    >7cn0B (B:)
hyspfkavwdwlilllviytavftpysaafllavvdlivdimfivdilinfrttyvnane
evvshpgriavhyfkgwflidmvaaipligllktarllrlvrvarkldrysgaavlfllm
ctfaliahwlaciwyaignmeqpigwlhnlgdqigkpggpsikdkyvtalyftfssltsv
gfgnvspntnsekifsicvmligslmyasifgnvsaiiqrl

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7cn0C (C:)
mpvrrghvapqntfldtiirkfegqsrkfiianarvencaviycndgfcelcgysraevm
qrpctcdflhgprtqrraaaqiaqallgaeerkveiafyrkdgscflclvdvvpvknedg
avimfilnfevvmekdmvgssptsdreiiapkikerthnvtekvtqvlslgadvlpeykl
qaprihrwtilhyspfkavwdwlilllviytavftpysaafllketeegppatecgyacq
plavvdlivdimfivdilinfrttyvnaneevvshpgriavhyfkgwflidmvaaipfdl
lifgsgseeligllktarllrlvrvarkldryseygaavlfllmctfaliahwlaciwya
ignmeqphmdsrigwlhnlgdqigkpynssglggpsikdkyvtalyftfssltsvgfgnv
spntnsekifsicvmligslmyasifgnvsaiiqrlysgtaryhtqmlrvrefirfhqip
nplrqrleeyfqhawsytngidmnavlkgfpeclqadiclhlnrsllqhckpfrgatkgc
lralamkfktthappgdtlvhagdlltalyfisrgsieilrgdvvvailgkndifgepln
lyarpgksngdvraltycdlhkihrddllevldmypefsdhfwssleitfnlrdtnmipg
grqyqelprcpaptpsllniplsspgrrprgdvesrldalqrqlnrletrlsadmatvlq
llqrqmtlvppaysavttpgpgptstspllpvsplptltldslsqvsqfmaceelppgap
elpqegptrrlslpgqlgaltsqplhrhgsdpgslevlfq

    Sequence, based on observed residues (ATOM records):
    >7cn0C (C:)
hyspfkavwdwlilllviytavftpysaafllavvdlivdimfivdilinfrttyvnane
evvshpgriavhyfkgwflidmvaaipligllktarllrlvrvarkldrysgaavlfllm
ctfaliahwlaciwyaignmeqpigwlhnlgdqigkpggpsikdkyvtalyftfssltsv
gfgnvspntnsekifsicvmligslmyasifgnvsaiiqrl

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7cn0D (D:)
mpvrrghvapqntfldtiirkfegqsrkfiianarvencaviycndgfcelcgysraevm
qrpctcdflhgprtqrraaaqiaqallgaeerkveiafyrkdgscflclvdvvpvknedg
avimfilnfevvmekdmvgssptsdreiiapkikerthnvtekvtqvlslgadvlpeykl
qaprihrwtilhyspfkavwdwlilllviytavftpysaafllketeegppatecgyacq
plavvdlivdimfivdilinfrttyvnaneevvshpgriavhyfkgwflidmvaaipfdl
lifgsgseeligllktarllrlvrvarkldryseygaavlfllmctfaliahwlaciwya
ignmeqphmdsrigwlhnlgdqigkpynssglggpsikdkyvtalyftfssltsvgfgnv
spntnsekifsicvmligslmyasifgnvsaiiqrlysgtaryhtqmlrvrefirfhqip
nplrqrleeyfqhawsytngidmnavlkgfpeclqadiclhlnrsllqhckpfrgatkgc
lralamkfktthappgdtlvhagdlltalyfisrgsieilrgdvvvailgkndifgepln
lyarpgksngdvraltycdlhkihrddllevldmypefsdhfwssleitfnlrdtnmipg
grqyqelprcpaptpsllniplsspgrrprgdvesrldalqrqlnrletrlsadmatvlq
llqrqmtlvppaysavttpgpgptstspllpvsplptltldslsqvsqfmaceelppgap
elpqegptrrlslpgqlgaltsqplhrhgsdpgslevlfq

    Sequence, based on observed residues (ATOM records):
    >7cn0D (D:)
hyspfkavwdwlilllviytavftpysaafllavvdlivdimfivdilinfrttyvnane
evvshpgriavhyfkgwflidmvaaipligllktarllrlvrvarkldrysgaavlfllm
ctfaliahwlaciwyaignmeqpigwlhnlgdqigkpggpsikdkyvtalyftfssltsv
gfgnvspntnsekifsicvmligslmyasifgnvsaiiqrl