PDB entry 7cml

View 7cml on RCSB PDB site
Description: The Crystal Structure of human JNK2 from Wuxi Biortus.
Class: transferase
Keywords: Protein kinase-like, transcription factor binding, TRANSFERASE
Deposited on 2020-07-28, released 2020-08-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-12, with a file datestamp of 2020-08-07.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK9, JNK2, PRKM9, SAPK1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P45984 (17-380)
      • engineered mutation (19)
      • engineered mutation (22)
      • engineered mutation (24)
      • engineered mutation (30)
      • engineered mutation (219-220)
      • engineered mutation (266-267)
    Domains in SCOPe 2.08: d7cmla_
  • Chain 'B':
    Compound: Mitogen-activated protein kinase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK9, JNK2, PRKM9, SAPK1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P45984 (17-380)
      • engineered mutation (19)
      • engineered mutation (22)
      • engineered mutation (24)
      • engineered mutation (30)
      • engineered mutation (219-220)
      • engineered mutation (266-267)
    Domains in SCOPe 2.08: d7cmlb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7cmlA (A:)
mggshhhhhhenlyfqgmskskvdnqfysvevadstftvlkryqqlkpigsgaqgivcaa
fdtvlginvavkklsrpfqnqthakrayrelvllkcvnhkniisllnvftpqktleefqd
vylvmelmdanlcqvihmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdc
tlkildfglartactnfmmtpyvvtryyrapevilgmgyaanvdiwsvgcimgelvkgcv
ifqgtdhidqwnkvieqlgtpsaefmaalqptvrnyvenrpkypgikfeelfpdwifpse
serdkiktsqardllskmlvidpdkrisvdealrhpyitvwydpaeaeapppqiydaqle
erehaieewkeliykevmdwe

    Sequence, based on observed residues (ATOM records): (download) 
    >7cmlA (A:)
mskskvdnqfysvevadstftvlkryqqlkpiaqgivcaafdtvlginvavkklsrpfqn
qthakrayrelvllkcvnhkniisllnvftpqktleefqdvylvmelmqvihmeldherm
syllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfgtryyrapevilgmgyaa
nvdiwsvgcimgelvkgcvifqgtdhidqwnkvieqlgtpsaefmaalqptvrnyvenrp
kypgikfeelfpdwifpseserdkiktsqardllskmlvidpdkrisvdealrhpyitvw
ydpaeaeapppqiydehaieewkeliykevmdwe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7cmlB (B:)
mggshhhhhhenlyfqgmskskvdnqfysvevadstftvlkryqqlkpigsgaqgivcaa
fdtvlginvavkklsrpfqnqthakrayrelvllkcvnhkniisllnvftpqktleefqd
vylvmelmdanlcqvihmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdc
tlkildfglartactnfmmtpyvvtryyrapevilgmgyaanvdiwsvgcimgelvkgcv
ifqgtdhidqwnkvieqlgtpsaefmaalqptvrnyvenrpkypgikfeelfpdwifpse
serdkiktsqardllskmlvidpdkrisvdealrhpyitvwydpaeaeapppqiydaqle
erehaieewkeliykevmdwe

    Sequence, based on observed residues (ATOM records): (download) 
    >7cmlB (B:)
mskskvdnqfysvevadstftvlkryqqlkpigaqgivcaafdtvlginvavkklsrpfq
nqthakrayrelvllkcvnhkniisllnvftpqktleefqdvylvmelmqvihmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfgtryyrapevilgmgya
anvdiwsvgcimgelvkgcvifqgtdhidqwnkvieqlgtpsaefmaalqptvrnyvenr
pkypgikfeelfpdwifpseserdkiktsqardllskmlvidpdkrisvdealrhpyitv
wydpaeaeapppqiydehaieewkeliykevmdwe