PDB entry 7cjt

View 7cjt on RCSB PDB site
Description: crystal structure of setdb1 tudor domain in complexed with (r,r)-59
Deposited on 2020-07-13, released 2021-04-14
The last revision was dated 2021-04-14, with a file datestamp of 2021-04-09.
Experiment type: XRAY
Resolution: 2.47 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase SETDB1
    Species: Homo sapiens [TaxId:9606]
    Gene: SETDB1, ESET, KIAA0067, KMT1E
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Histone-lysine N-methyltransferase SETDB1
    Species: Homo sapiens [TaxId:9606]
    Gene: SETDB1, ESET, KIAA0067, KMT1E
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15047 (19-End)
      • expression tag (18)
  • Chain 'C':
    Compound: Histone-lysine N-methyltransferase SETDB1
    Species: Homo sapiens [TaxId:9606]
    Gene: SETDB1, ESET, KIAA0067, KMT1E
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15047 (19-End)
      • expression tag (18)
  • Chain 'D':
    Compound: Histone-lysine N-methyltransferase SETDB1
    Species: Homo sapiens [TaxId:9606]
    Gene: SETDB1, ESET, KIAA0067, KMT1E
    Database cross-references and differences (RAF-indexed):
  • Heterogens: G09, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7cjtA (A:)
gsshhhhhhssgenlyfqggelskdgdlivsmrilgkkrtktwhkgtliaiqtvgpgkky
kvkfdnkgksllsgnhiaydyhppadklyvgsrvvakykdgnqvwlyagivaetpnvknk
lrfliffddgyasyvtqselypicrplkktwediediscrdfieeyvtaypnrpmvllks
gqliktewegtwwksrveevdgslvrilflddkrcewiyrgstrlepmfsmktssasale

    Sequence, based on observed residues (ATOM records):
    >7cjtA (A:)
lskdgdlivsmrilgkkrtktwhkgtliaiqtvgpgkkykvkfdnkgksllsgnhiaydy
hppadklyvgsrvvakykdgnqvwlyagivaetpnvknklrfliffddgyasyvtqsely
picrplkktwediediscrdfieeyvtaypnrpmvllksgqliktewegtwwksrveevd
gslvrilflddkrcewiyrgstrlepmfsmkt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7cjtB (B:)
gsshhhhhhssgenlyfqggelskdgdlivsmrilgkkrtktwhkgtliaiqtvgpgkky
kvkfdnkgksllsgnhiaydyhppadklyvgsrvvakykdgnqvwlyagivaetpnvknk
lrfliffddgyasyvtqselypicrplkktwediediscrdfieeyvtaypnrpmvllks
gqliktewegtwwksrveevdgslvrilflddkrcewiyrgstrlepmfsmktssasale

    Sequence, based on observed residues (ATOM records):
    >7cjtB (B:)
ggelskdgdlivsmrilgkkrtktwhkgtliaiqtvgpgkkykvkfdnkgksllsgnhia
ydyhppadklyvgsrvvakykdgnqvwlyagivaetpnvknklrfliffddgyasyvtqs
elypicrplkktwediediscrdfieeyvtaypnrpmvllksgqliktewegtwwksrve
evdgslvrilflddkrcewiyrgstrlepmfsmkt

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7cjtC (C:)
gsshhhhhhssgenlyfqggelskdgdlivsmrilgkkrtktwhkgtliaiqtvgpgkky
kvkfdnkgksllsgnhiaydyhppadklyvgsrvvakykdgnqvwlyagivaetpnvknk
lrfliffddgyasyvtqselypicrplkktwediediscrdfieeyvtaypnrpmvllks
gqliktewegtwwksrveevdgslvrilflddkrcewiyrgstrlepmfsmktssasale

    Sequence, based on observed residues (ATOM records):
    >7cjtC (C:)
ggelskdgdlivsmrilgkkrtktwhkgtliaiqtvgpgkkykvkfdnkgksllsgnhia
ydyhppadklyvgsrvvakykdgnqvwlyagivaetpnvknklrfliffddgyasyvtqs
elypicrplkktwediediscrdfieeyvtaypnrpmvllksgqliktewegtwwksrve
evdgslvrilflddkrcewiyrgstrlepmfsmkt

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7cjtD (D:)
gsshhhhhhssgenlyfqggelskdgdlivsmrilgkkrtktwhkgtliaiqtvgpgkky
kvkfdnkgksllsgnhiaydyhppadklyvgsrvvakykdgnqvwlyagivaetpnvknk
lrfliffddgyasyvtqselypicrplkktwediediscrdfieeyvtaypnrpmvllks
gqliktewegtwwksrveevdgslvrilflddkrcewiyrgstrlepmfsmktssasale

    Sequence, based on observed residues (ATOM records):
    >7cjtD (D:)
lskdgdlivsmrilgkkrtktwhkgtliaiqtvgpgkkykvkfdnkgksllsgnhiaydy
hppadklyvgsrvvakykdgnqvwlyagivaetpnvknklrfliffddgyasyvtqsely
picrplkktwediediscrdfieeyvtaypnrpmvllksgqliktewegtwwksrveevd
gslvrilflddkrcewiyrgstrlepmfsmkt