PDB entry 7cfo

View 7cfo on RCSB PDB site
Description: Crystal structure of human RXRalpha ligand binding domain complexed with CBTF-EE.
Class: nuclear protein
Keywords: Retinoid X receptor alpha, antagonist, NUCLEAR PROTEIN
Deposited on 2020-06-27, released 2021-01-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-27, with a file datestamp of 2021-01-22.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinoic acid receptor RXR-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Retinoic acid receptor RXR-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cfob_
  • Chain 'C':
    Compound: Retinoic acid receptor RXR-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7cfoc_
  • Chain 'D':
    Compound: Retinoic acid receptor RXR-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GOL, WZ6, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7cfoB (B:)
gsshssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftl
vewakriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahs
agvgaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyas
leayckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaph
qmt

    Sequence, based on observed residues (ATOM records): (download) 
    >7cfoB (B:)
pverileaelapvtnicqaadkqlftlvewakriphfselplddqvillragwnellias
fshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktelgclra
ivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalrsiglkc
lehlfffkligdtpidtflmemleap

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7cfoC (C:)
gsshssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftl
vewakriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahs
agvgaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyas
leayckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaph
qmt

    Sequence, based on observed residues (ATOM records): (download) 
    >7cfoC (C:)
pverileaelavepvtnicqaadkqlftlvewakriphfselplddqvillragwnelli
asfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktelgcl
raivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalrsigl
kclehlfffkligdtpidtflmemle

  • Chain 'D':
    No sequence available.