PDB entry 7c7f

View 7c7f on RCSB PDB site
Description: Crystal structures of AKR1C3 binary complex with NADP+
Class: oxidoreductase
Keywords: Cancer, OXIDOREDUCTASE
Deposited on 2020-05-25, released 2020-09-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-07, with a file datestamp of 2020-10-02.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aldo-keto reductase family 1 member C3
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1C3, DDH1, HSD17B5, KIAA0119, PGFS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7c7fa_
  • Chain 'B':
    Compound: Aldo-keto reductase family 1 member C3
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1C3, DDH1, HSD17B5, KIAA0119, PGFS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7c7fb_
  • Heterogens: NAP, EDO, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7c7fA (A:)
gsmdskhqcvklndghfmpvlgfgtyappevprskalevtklaieagfrhidsahlynne
eqvglairskiadgsvkredifytsklwstfhrpelvrpalenslkkaqldyvdlylihs
pmslkpgeelsptdengkvifdivdlcttweamekckdaglaksigvsnfnrrqlemiln
kpglkykpvcnqvechpyfnrsklldfckskdivlvaysalgsqrdkrwvdpnspvlled
pvlcalakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltaedmkaidg
ldrnlhyfnsdsfashpnypysdey

    Sequence, based on observed residues (ATOM records): (download) 
    >7c7fA (A:)
hqcvklndghfmpvlgfgtyappevprskalevtklaieagfrhidsahlynneeqvgla
irskiadgsvkredifytsklwstfhrpelvrpalenslkkaqldyvdlylihspmslkp
geelsptdengkvifdivdlcttweamekckdaglaksigvsnfnrrqlemilnkpglky
kpvcnqvechpyfnrsklldfckskdivlvaysalgsqrdkrwvdpnspvlledpvlcal
akkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltaedmkaidgldrnlh
yfnsdsfashpnypysdey

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7c7fB (B:)
gsmdskhqcvklndghfmpvlgfgtyappevprskalevtklaieagfrhidsahlynne
eqvglairskiadgsvkredifytsklwstfhrpelvrpalenslkkaqldyvdlylihs
pmslkpgeelsptdengkvifdivdlcttweamekckdaglaksigvsnfnrrqlemiln
kpglkykpvcnqvechpyfnrsklldfckskdivlvaysalgsqrdkrwvdpnspvlled
pvlcalakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltaedmkaidg
ldrnlhyfnsdsfashpnypysdey

    Sequence, based on observed residues (ATOM records): (download) 
    >7c7fB (B:)
hqcvklndghfmpvlgfgtyappevprskalevtklaieagfrhidsahlynneeqvgla
irskiadgsvkredifytsklwstfhrpelvrpalenslkkaqldyvdlylihspmslkp
geelsptdengkvifdivdlcttweamekckdaglaksigvsnfnrrqlemilnkpglky
kpvcnqvechpyfnrsklldfckskdivlvaysalgsqrdkrwvdpnspvlledpvlcal
akkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltaedmkaidgldrnlh
yfnsdsfashpnypysdey