PDB entry 7c76

View 7c76 on RCSB PDB site
Description: cryo-em structure of human tlr3 in complex with unc93b1
Deposited on 2020-05-23, released 2021-01-06
The last revision was dated 2021-02-24, with a file datestamp of 2021-02-19.
Experiment type: EM
Resolution: 3.4 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Toll-like receptor 3
    Species: Homo sapiens [TaxId:9606]
    Gene: TLR3
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Protein unc-93 homolog B1
    Species: Homo sapiens [TaxId:9606]
    Gene: UNC93B1, UNC93, UNC93B
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7c76A (A:)
mrqtlpciyfwggllpfgmlcassttkctvshevadcshlkltqvpddlptnitvlnlth
nqlrrlpaanftrysqltsldvgfntisklepelcqklpmlkvlnlqhnelsqlsdktfa
fctnltelhlmsnsiqkiknnpfvkqknlitldlshnglsstklgtqvqlenlqelllsn
nkiqalkseeldifansslkklelssnqikefspgcfhaigrlfglflnnvqlgpsltek
lclelantsirnlslsnsqlsttsnttflglkwtnltmldlsynnlnvvgndsfawlpql
eyffleynniqhlfshslhglfnvrylnlkrsftkqsislaslpkiddfsfqwlkclehl
nmedndipgiksnmftglinlkylslsnsftslrtltnetfvslahsplhilnltknkis
kiesdafswlghlevldlglneigqeltgqewrglenifeiylsynkylqltrnsfalvp
slqrlmlrrvalknvdsspspfqplrnltildlsnnnianinddmleglekleildlqhn
nlarlwkhanpggpiyflkglshlhilnlesngfdeipvevfkdlfelkiidlglnnlnt
lpasvfnnqvslkslnlqknlitsvekkvfgpafrnlteldmrfnpfdctcesiawfvnw
inethtnipelsshylcntpphyhgfpvrlfdtssckdsapfelffmintsillififiv
llihfegwrisfywnvsvhrvlgfkeidrqteqfeyaayiihaykdkdwvwehfssmeke
dqslkfcleerdfeagvfeleaivnsikrsrkiifvithhllkdplckrfkvhhavqqai
eqnldsiilvfleeipdyklnhalclrrgmfkshcilnwpvqkerigafrhklqvalgsk
nsvh

    Sequence, based on observed residues (ATOM records):
    >7c76A (A:)
vshevadcshlkltqvpddlptnitvlnlthnqlrrlpaanftrysqltsldvgfntisk
lepelcqklpmlkvlnlqhnelsqlsdktfafctnltelhlmsnsiqkiknnpfvkqknl
itldlshnglsstklgtqvqlenlqelllsnnkiqalkseeldifansslkklelssnqi
kefspgcfhaigrlfglflnnvqlgpslteklclelantsirnlslsnsqlsttsnttfl
glkwtnltmldlsynnlnvvgndsfawlpqleyffleynniqhlfshslhglfnvrylnl
krsftkqlpkiddfsfqwlkclehlnmedndipgiksnmftglinlkylslsnsftslrt
ltnetfvslahsplhilnltknkiskiesdafswlghlevldlglneigqeltgqewrgl
enifeiylsynkylqltrnsfalvpslqrlmlrrvalknvdsspspfqplrnltildlsn
nnianinddmleglekleildlqhnnlarlwkhanpggpiyflkglshlhilnlesngfd
eipvevfkdlfelkiidlglnnlntlpasvfnnqvslkslnlqknlitsvekkvfgpafr
nlteldmrfnpfdctcesiawfvnwinethtnipelsshylcntpphyhgfpvrlfdtss
ckdsapfelffmintsillififivllihfe

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7c76B (B:)
meaepplypmagaagpqgdedllgvpdgpeapldelvgaypnyneeeeerryyrrkrlgv
lknvlaasaggmltygvylgllqmqlilhydetyrevkygnmglpdidskmlmginvtpi
aallytpvlirffgtkwmmflavgiyalfvstnyweryytlvpsavalgmaivplwasmg
nyitrmaqkyheyshykeqdgqgmkqrpprgshapyllvfqaifysffhlsfacaqlpmi
yflnhylydlnhtlynvqscgtnshgilsgfnktvlrtlprsgnlivvesvlmavaflam
llvlglcgaayrpteeidlrsvgwgnifqlpfkhvrdyrlrhlvpffiysgfevlfactg
ialgygvcsvglerlayllvayslgasaasllgllglwlprpvplvagagvhllltfilf
fwapvprvlqhswilyvaaalwgvgsalnktglstllgilyedkerqdfiftiyhwwqav
aiftvylgsslhmkaklavllvtlvaaavsylrmeqklrrgvaprqpriprpqhkvrgyr
yleednsdesdaegehgdgaeeeappagprpgpepaglgrrpcpyeqaqggdgpeeq

    Sequence, based on observed residues (ATOM records):
    >7c76B (B:)
eeeeerryyrrkrlgvlknvlaasaggmltygvylgllqmqlilhydetyrevkygnmgl
pdidskmlmginvtpiaallytpvlirffgtkwmmflavgiyalfvstnyweryytlvps
avalgmaivplwasmgnyitrmaqkyheyshykeqdgqgmkqrpprgshapyllvfqaif
ysffhlsfacaqlpmiyflnhylydlnhtlynvqscgtnshgilsgfnktvlrtlprsgn
livvesvlmavaflamllvlglcgaayrpteeidlrsvgwgnifqlpfkhvrdyrlrhlv
pffiysgfevlfactgialgygvcsvglerlayllvayslgasaasllgllglwlprpvp
lvagagvhllltfilffwapvprvlqhswilyvaaalwgvgsalnktglstllgilyedk
erqdfiftiyhwwqavaiftvylgsslhmkaklavllvtlvaaavsylrmeqklrrgvap
rqp