PDB entry 7c2j

View 7c2j on RCSB PDB site
Description: Crystal structure of nsp16-nsp10 heterodimer from SARS-CoV-2 in complex with SAM (without additional SAM during crystallization)
Class: viral protein
Keywords: 2'-O-Methylase, VIRAL PROTEIN
Deposited on 2020-05-07, released 2020-05-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-10, with a file datestamp of 2021-03-05.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2'-O-methyltransferase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7c2ja_
  • Chain 'B':
    Compound: non-structural protein 10
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7c2jb_
  • Heterogens: SAM, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7c2jA (A:)
mhhhhhhssqawqpgvampnlykmqrmllekcdlqnygdsatlpkgimmnvakytqlcqy
lntltlavpynmrvihfgagsdkgvapgtavlrqwlptgtllvdsdlndfvsdadstlig
dcatvhtankwdliisdmydpktknvtkendskegfftyicgfiqqklalggsvaikite
hswnadlyklmghfawwtafvtnvnassseafligcnylgkpreqidgyvmhanyifwrn
tnpiqlssyslfdmskfplklrgtavmslkegqindmilsllskgrliirennrvvissd
vlvnn

    Sequence, based on observed residues (ATOM records): (download) 
    >7c2jA (A:)
ssqawqpgvampnlykmqrmllekcdlqnygdsatlpkgimmnvakytqlcqylntltla
vpynmrvihfgagsdkgvapgtavlrqwlptgtllvdsdlndfvsdadstligdcatvht
ankwdliisdmydpktknvtkendskegfftyicgfiqqklalggsvaikitehswnadl
yklmghfawwtafvtnvnassseafligcnylgkpreqidgyvmhanyifwrntnpiqls
syslfdmskfplklrgtavmslkegqindmilsllskgrliirennrvvissdvlvnn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7c2jB (B:)
gplgsagnatevpanstvlsfcafavdaakaykdylasggqpitncvkmlcthtgtgqai
tvtpeanmdqesfggascclycrchidhpnpkgfcdlkgkyvqipttcandpvgftlknt
vctvcgmwkgygcscdqlrepmlq

    Sequence, based on observed residues (ATOM records): (download) 
    >7c2jB (B:)
favdaakaykdylasggqpitncvkmlcthtgtgqaitvtpeanmdqesfggascclycr
chidhpnpkgfcdlkgkyvqipttcandpvgftlkntvctvcgmwkgygcscdql