PDB entry 7c19

View 7c19 on RCSB PDB site
Description: Crystal structure of a dinucleotide-binding protein (Y224A/Y246A) of ABC transporter endogenously bound to uridylyl-3'-5'-phospho-guanosine (Form II)
Class: transport protein
Keywords: c-di-GMP/AMP, Substrate-binding protein, Thermus thermophilus, tRNA synthesis and/or modification, Venus Fly-trap mechanism, UgpB, TRANSPORT PROTEIN
Deposited on 2020-05-02, released 2021-03-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-10, with a file datestamp of 2021-03-05.
Experiment type: XRAY
Resolution: 1.77 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sugar ABC transporter, periplasmic sugar-binding protein
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Gene: TTHA0379
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SLB4 (2-End)
      • expression tag (1)
      • engineered mutation (225)
      • engineered mutation (247)
    Domains in SCOPe 2.08: d7c19a1, d7c19a2
  • Chain 'B':
    Compound: Sugar ABC transporter, periplasmic sugar-binding protein
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Gene: TTHA0379
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SLB4 (2-End)
      • expression tag (1)
      • engineered mutation (225)
      • engineered mutation (247)
    Domains in SCOPe 2.08: d7c19b1, d7c19b2
  • Heterogens: FGO, CL, CO2, PO2, PEG, CO3, EDO, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7c19A (A:)
mmkpedvikeqcarakvvaelwhgftggapkaalenlvvefnkaqqgrcvrpvpqggyrd
lstkikaafaagkvptmaqafennialyleakallpieslgvklqgvnltflnavrfggv
vygvpfnksiqvlyynkdllkkhgvpvpatleefvaaakklsraeggpvywfqpdastfa
yfffnlggsylkdgklvlnskeavealtllqngvkegwakpitsgainqnlgsgpyafsv
dtsagytaylraakfdlgvatlpgrtkgqpgyglvqgtnlvvfrqaskeeqavakdflef
vlspraqavfatatgyvpvtegalkdpvyqayaaenpdyativrqsryakfepalaeweq
irfdilgqaikeailnkadpkaaldraqklaedllssrtrhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7c19A (A:)
mkpedvikeqcarakvvaelwhgftggapkaalenlvvefnkaqqgrcvrpvpqggyrdl
stkikaafaagkvptmaqafennialyleakallpieslgvklqgvnltflnavrfggvv
ygvpfnksiqvlyynkdllkkhgvpvpatleefvaaakklsraeggpvywfqpdastfay
fffnlggsylkdgklvlnskeavealtllqngvkegwakpitsgainqnlgsgpyafsvd
tsagytaylraakfdlgvatlpgrtkgqpgyglvqgtnlvvfrqaskeeqavakdflefv
lspraqavfatatgyvpvtegalkdpvyqayaaenpdyativrqsryakfepalaeweqi
rfdilgqaikeailnkadpkaaldraqklaedlls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7c19B (B:)
mmkpedvikeqcarakvvaelwhgftggapkaalenlvvefnkaqqgrcvrpvpqggyrd
lstkikaafaagkvptmaqafennialyleakallpieslgvklqgvnltflnavrfggv
vygvpfnksiqvlyynkdllkkhgvpvpatleefvaaakklsraeggpvywfqpdastfa
yfffnlggsylkdgklvlnskeavealtllqngvkegwakpitsgainqnlgsgpyafsv
dtsagytaylraakfdlgvatlpgrtkgqpgyglvqgtnlvvfrqaskeeqavakdflef
vlspraqavfatatgyvpvtegalkdpvyqayaaenpdyativrqsryakfepalaeweq
irfdilgqaikeailnkadpkaaldraqklaedllssrtrhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7c19B (B:)
mkpedvikeqcarakvvaelwhgftggapkaalenlvvefnkaqqgrcvrpvpqggyrdl
stkikaafaagkvptmaqafennialyleakallpieslgvklqgvnltflnavrfggvv
ygvpfnksiqvlyynkdllkkhgvpvpatleefvaaakklsraeggpvywfqpdastfay
fffnlggsylkdgklvlnskeavealtllqngvkegwakpitsgainqnlgsgpyafsvd
tsagytaylraakfdlgvatlpgrtkgqpgyglvqgtnlvvfrqaskeeqavakdflefv
lspraqavfatatgyvpvtegalkdpvyqayaaenpdyativrqsryakfepalaeweqi
rfdilgqaikeailnkadpkaaldraqklaedllss