PDB entry 7buc

View 7buc on RCSB PDB site
Description: Crystal structure of EHMT2 SET domain in complex with compound 13
Class: transferase/transferase inhibitor
Keywords: protein-small molecule inhibitor complex, transferase-transferase inhibitor complex
Deposited on 2020-04-06, released 2020-11-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-16, with a file datestamp of 2021-06-11.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase EHMT2
    Species: Homo sapiens [TaxId:9606]
    Gene: EHMT2, BAT8, C6orf30, G9A, KMT1C, NG36
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7buca_
  • Chain 'B':
    Compound: Histone-lysine N-methyltransferase EHMT2
    Species: Homo sapiens [TaxId:9606]
    Gene: EHMT2, BAT8, C6orf30, G9A, KMT1C, NG36
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7bucb_
  • Heterogens: F80, ZN, SAM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7bucA (A:)
gsnrairtekiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnith
lqhctcvddcsssnclcgqlsircwydkdgrllqefnkiepplifecnqacscwrncknr
vvqsgikvrlqlyrtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdld
nkdgevycidaryygnisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeel
gfdygdrfwdikskyftcqcgsekckhsaeaialeqsrlarld

    Sequence, based on observed residues (ATOM records): (download) 
    >7bucA (A:)
tekiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnithlqhctcv
ddcsssnclcgqlsircwydkdgrllqefnkiepplifecnqacscwrncknrvvqsgik
vrlqlyrtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdldnkdgevy
cidaryygnisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeelgfdygdr
fwdikskyftcqcgsekckhsaeaialeqsrla

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7bucB (B:)
gsnrairtekiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnith
lqhctcvddcsssnclcgqlsircwydkdgrllqefnkiepplifecnqacscwrncknr
vvqsgikvrlqlyrtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdld
nkdgevycidaryygnisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeel
gfdygdrfwdikskyftcqcgsekckhsaeaialeqsrlarld

    Sequence, based on observed residues (ATOM records): (download) 
    >7bucB (B:)
tekiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnithlqhctcv
ddcsssnclcgqlsircwydkdgrllqefnkiepplifecnqacscwrncknrvvqsgik
vrlqlyrtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdldevycida
ryygnisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeelgfdygdrfwdi
kskyftcqcgsekckhsaeaialeqsrla