PDB entry 7bsu

View 7bsu on RCSB PDB site
Description: cryo-em structure of a human atp11c-cdc50a flippase in ptdser-bound e2bef state
Deposited on 2020-03-31, released 2020-09-30
The last revision was dated 2020-10-14, with a file datestamp of 2020-10-09.
Experiment type: EM
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: atp11c
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7BSU (Start-1083)
  • Chain 'C':
    Compound: Cell cycle control protein 50A
    Species: Homo sapiens [TaxId:9606]
    Gene: TMEM30A, C6orf67, CDC50A
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NV96
      • engineered mutation (174)
      • engineered mutation (189)
      • engineered mutation (291)
  • Heterogens: P5S, BFD, MG, NAG, AH2

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7bsuA (A:)
rfcageekrvgtrtvfvgnhpvseteayiaqrfcdnrivsskytlwnflpknlfeqfrri
anfyfliiflvqvtvdtptspvtsglplffvitvtaikqgyedwlrhradnevnkstvyi
ienakrvrkesekikvgdvvevqadetfpcdlillsscttdgtcyvttasldgesnckth
yavrdtialctaesidtlraaieceqpqpdlykfvgriniysnsleavarslgpenlllk
gatlkntekiygvavytgmetkmalnyqgksqkrsaveksinaflivylfilltkaavct
tlkyvwqstpyndepwynqktqkeretlkvlkmftdflsfmvlfnfiipvsmyvtvemqk
flgsffiswdkdfydeeinegalvntsdlneelgqvdyvftdktgtltensmefieccid
ghkykgvtqevdglsqtdgtltyfdkvdknreelflralclchtveiktndavdgatesa
eltyissspdeialvkgakrygftflgnrngymrvenqrkeieeyellhtlnfdavrrrm
svivktqegdillfckgadsavfprvqnheieltkvhvernamdgyrtlcvafkeiapdd
yerinrqlieakmalqdreekmekvfddietnmnligatavedklqdqaaetiealhaag
lkvwvltgdkmetakstcyacrlfqtntellelttktieeserkedrlhellieyrkkll
hefpkstrsfkkawtehqeygliidgstlslilnssqdsssnnyksiflqicmkctavlc
crmaplqkaqivrmvknlkgspitlsigdgandvsmileshvgigikgkegrqaarnsdy
svpkfkhlkklllahghlyyvriahlvqyffyknlcfilpqflyqffcgfsqqplydaay
ltmynicftslpilayslleqhinidtltsdprlymkisgnamlqlgpflywtflaafeg
tvfffgtyflfqtasleengkvygnwtfgtivftvlvftvtlklaldtrfwtwinhfviw
gslafyvffsffwggiiwpflkqqrmyfvfaqmlssvstwlaiillifislfpeillivl
knvr

    Sequence, based on observed residues (ATOM records):
    >7bsuA (A:)
trtvfvgnhpvqrfcdnrivsskytlwnflpknlfeqfrrianfyfliiflvqvtvdtpt
spvtsglplffvitvtaikqgyedwlrhradnevnkstvyiienakrvrkesekikvgdv
vevqadetfpcdlillsscttdgtcyvttasldgesnckthyavrdtialctaesidtlr
aaieceqpqpdlykfvgriniysnsleavarslgpenlllkgatlkntekiygvavytgm
etkmalnyqgksqkrsaveksinaflivylfilltkaavcttlkyvwqstpyndepwynq
ktqkeretlkvlkmftdflsfmvlfnfiipvsmyvtvemqkflgsffiswdkdfydeein
egalvntsdlneelgqvdyvftdktgtltklqdqaaetiealhaaglkvwvltgdkmeta
kstcyacrlfqtntellelttktieeserkedrlhellieyrkklehqeygliidgstls
lilnssqdsssnnyksiflqicmkctavlccrmaplqkaqivrmvknlkgspitlsigdg
andvsmileshvgigikgkegrqaarnsdysvpkfkhlkklllahghlyyvriahlvqyf
fyknlcfilpqflyqffcgfsqqplydaayltmynicftslpilayslleqhinidtlts
dprlymkisgnamlqlgpflywtflaafegtvfffgtyflfqtasleengkvygnwtfgt
ivftvlvftvtlklaldtrfwtwinhfviwgslafyvffsffwggiiwpflkqqrmyfvf
aqmlssvstwlaiillifislfpeillivlknvr

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7bsuC (C:)
mamnynakdevdggppcapggtaktrrpdntafkqqrlpawqpiltagtvlpiffiigli
fipigigifvtsnnireieidytgtepsspcnkclspdvtpcfctinftleksfegnvfm
yyglsnfyqnhrryvksrddsqlngdssallnpskecepyrrnedkpiapcgaimnsmfn
dtlelfligqdsypipialkkkgiawwtdknvkfrnppggdnleerfkgttkpvnwlkpv
ymldsdpdnngfinedfivwmrtaalptfrklyrlierksdlhptlpagrywlnvtynyp
vhyfdgrkrmilstiswmggknpflgiayiavgsisfllgvvllvinhkyrnssntadit
i

    Sequence, based on observed residues (ATOM records):
    >7bsuC (C:)
rpdntafkqqrlpawqpiltagtvlpiffiiglifipigigifvtsnnireieidytgte
psspcnkclspdvtpcfctinftleksfegnvfmyyglsnfyqnhrryvksrddsqlngd
ssallnpskecepyrrnedkpiapcgaimnsmfndtlelfligqdsypipialkkkgiaw
wtdknvkfrnppggdnleerfkgttkpvnwlkpvymldsdpdnngfinedfivwmrtaal
ptfrklyrlierksdlhptlpagrywlnvtynypvhyfdgrkrmilstiswmggknpflg
iayiavgsisfllgvvllvinhky