PDB entry 7bot

View 7bot on RCSB PDB site
Description: human sirt2 in complex with myristoyl thiourea inhibitor, no.23
Deposited on 2020-03-19, released 2021-03-24
The last revision was dated 2021-10-06, with a file datestamp of 2021-10-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nad-dependent protein deacetylase sirtuin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT2, SIR2L, SIR2L2
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: myristoyl thiourea inhibitor, No.23
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 7BOT (0-End)
  • Heterogens: P6S, F4R, AIB, NH2, ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7botA (A:)
gsqkerlldeltlegvarymqsercrrviclvgagistsagipdfrspstglydnlekyh
lpypeaifeisyfkkhpepffalakelypgqfkptichyfmrllkdkglllrcytqnidt
leriagleqedlveahgtfytshcvsascrheyplswmkekifsevtpkcedcqslvkpd
ivffgeslparffscmqsdflkvdlllvmgtslqvqpfasliskaplstprllinkekag
gggmdfdskkayrdvawlgecdqgclalaellgwkkeledlvrrehasidaqs

    Sequence, based on observed residues (ATOM records):
    >7botA (A:)
erlldeltlegvarymqsercrrviclvgagistsagipdfrspydnleklpypeaifei
syfkkhpepffalakelypgqfkptichyfmrllkdkglllrcytqnidtleriagleqe
dlveahgtfytshcvsascrheyplswmkekifsevtpkcedclvkpdivffgeslparf
fscmqsdflkvdlllvmgtslqvqpfasliskaplstprllinkekagmdfdskkayrdv
awlgecdqgclalaellgwkkeledlvrrehasidaq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >7botB (B:)
xkar