PDB entry 7bci

View 7bci on RCSB PDB site
Description: Notum Fragment 784
Class: hydrolase
Keywords: Notum Inhibitor, HYDROLASE
Deposited on 2020-12-19, released 2022-01-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-01-12, with a file datestamp of 2022-01-07.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Palmitoleoyl-protein carboxylesterase NOTUM
    Species: Homo sapiens [TaxId:9606]
    Gene: NOTUM, OK/SW-CL.30
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6P988 (3-373)
      • cloning artifact (0-2)
      • engineered mutation (252)
      • expression tag (374-382)
    Domains in SCOPe 2.08: d7bcia_
  • Heterogens: GVV, SO4, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7bciA (A:)
etgsaqqlnedlrlhlllntsvtcndgspagyylkesrgsrrwllfleggwycfnrencd
srydtmrrlmssrdwprtrtgtgilssqpeenpywwnanmvfipycssdvwsgassksek
neyafmgaliiqevvrellgrglsgakvlllagssaggtgvllnvdrvaeqleklgypai
qvrgladsgwfldnkqyrhtdcvdtitcapteairrgirywngvvpercrrqfqegeewn
cffgykvyptlrspvfvvqwlfdeaqltvdnvhltgqpvqeglrlyiqnlgrelrhtlkd
vpasfapaclsheiiirshwtdvqvkgtslpralhcwdrslhdshkasktplkgcpvhlv
dscpwphcnpscptgtkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7bciA (A:)
dlrlhlllntsvtcndgspagyylkesrgsrrwllfleggwycfnrencdsrydtmrrlm
ssrdwprtrtgtgilssqpeenpywwnanmvfipycssdvwsgassksekneyafmgali
iqevvrellgrglsgakvlllagssaggtgvllnvdrvaeqleklgypaiqvrgladsgw
fldnkqyrpteairrgirywngvvpercrrqfqegeewncffgykvyptlrspvfvvqwl
fdeaqltvdnvhvqeglrlyiqnlgrelrhtlkdvpasfapaclsheiiirshwtdvqvk
gtslpralhcwdrslplkgcpvhlvdscpwphcnpscp