PDB entry 7bc7

View 7bc7 on RCSB PDB site
Description: cryo-em structure of the proton coupled folate transporter at ph 6.0 bound to pemetrexed
Deposited on 2020-12-18, released 2021-05-12
The last revision was dated 2021-08-11, with a file datestamp of 2021-08-06.
Experiment type: EM
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proton-coupled folate transporter
    Species: Gallus gallus [TaxId:9031]
    Gene: PCFT
    Database cross-references and differences (RAF-indexed):
    • Uniprot E6Y8U5 (0-472)
      • expression tag (473-479)
  • Chain 'B':
    Compound: Nanobody
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 7BC7 (0-122)
  • Heterogens: LYA

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7bc7A (A:)
maapsdpptaatppapppparrclpapsvepllflatlalglqvplatqylwdrlgaerg
yvgpnassphgcgngsgavdplreevealvahwnlcinlggffvglfsvtlfgpwsdsvg
rrpvlvlpavgmavqaavyllvmylrlhvaylllgriisgllgdynlilagcfasvadss
nqrtrtfrvaileaclgvagmvasvgggqwrkaegyinpfwlvlaaslaaalyaalclqe
tvkqrraaklltlqhykavyklytapedlssrrklalyslaffllvtvhfgtkdlyvlye
lgsplcwasdligygsaasylaylsslgglrllqlcledtwvaeiglisniaglvvisla
tttplmftgygimflsmaatpviraklsklvseteqgalfasvacveglcslvatgvfns
lypstlhfmrgfpflfgailllipaaimgwieiqdsnlqyshfsdassspadggenlyfq

    Sequence, based on observed residues (ATOM records):
    >7bc7A (A:)
apsvepllflatlalglqvplatqylwdrlgaergyvgpnassphgcgngsgavdplree
vealvahwnlcinlggffvglfsvtlfgpwsdsvgrrpvlvlpavgmavqaavyllvmyl
rlhvaylllgriisgllgdynlilagcfasvadssnqrtrtfrvaileaclgvagmvasv
gggqwrkaegyinpfwlvlaaslaaalyaalclqetvkqrraaklltlqhykavyklyta
pedlssrrklalyslaffllvtvhfgtkdlyvlyelgsplcwasdligygsaasylayls
slgglrllqlcledtwvaeiglisniaglvvislatttplmftgygimflsmaatpvira
klsklvseteqgalfasvacveglcslvatgvfnslypstlhfmrgfpflfgailllipa
aimgwieiqdsn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7bc7B (B:)
gpsqvqlvesggglvqpggslrlscaasgftfsrywmywvrqapgkgpewlshmnpsgsd
ikytdsvkgrftisrdnakntlylqmnslkpddtavyycvadrralgspeywgqgtqvtv
ssa

    Sequence, based on observed residues (ATOM records):
    >7bc7B (B:)
vqlvesggglvqpggslrlscaasgftfsrywmywvrqapgkgpewlshmnpsgsdikyt
dsvkgrftisrdnakntlylqmnslkpddtavyycvadrralgspeywgqgtqvtvs