PDB entry 7b9h

View 7b9h on RCSB PDB site
Description: Crystal structure of the PDE4D catalytic domain in complex with GEBR-42a
Class: hydrolase
Keywords: Phosphodiesterase 4D, Inhibitor, Complex, GEBR, HYDROLASE
Deposited on 2020-12-14, released 2021-06-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-06-30, with a file datestamp of 2021-06-25.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE4D, DPDE3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d7b9ha_
  • Chain 'B':
    Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE4D, DPDE3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08499 (Start-335)
      • expression tag (336-337)
    Domains in SCOPe 2.07: d7b9hb1, d7b9hb2
  • Heterogens: T3K, ZN, MG, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7b9hA (A:)
msiprfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfk
ipvdtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifa
saihdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkq
rqslrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhc
adlsnptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyi
vhplwetwadlvhpdaqdildtlednrewyqstipqahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7b9hA (A:)
prfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipv
dtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasai
hdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqs
lrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadl
snptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhp
lwetwadlvhpdaqdildtlednrewyqstip

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7b9hB (B:)
msiprfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfk
ipvdtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifa
saihdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkq
rqslrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhc
adlsnptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyi
vhplwetwadlvhpdaqdildtlednrewyqstipqahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7b9hB (B:)
qedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdtlitylm
tledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihdvdhpgv
snqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslrkmvidi
vlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadlsnptkplq
lyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplwetwadl
vhpdaqdildtlednrewyqstipqah