PDB entry 7b65

View 7b65 on RCSB PDB site
Description: structure of nudt15 r139c mutant in complex with th7755
Deposited on 2020-12-07, released 2021-03-24
The last revision was dated 2021-07-21, with a file datestamp of 2021-07-16.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nucleotide triphosphate diphosphatase NUDT15
    Species: Homo sapiens [TaxId:9606]
    Gene: NUDT15, MTH2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NV35 (0-163)
      • engineered mutation (138)
  • Chain 'B':
    Compound: Nucleotide triphosphate diphosphatase NUDT15
    Species: Homo sapiens [TaxId:9606]
    Gene: NUDT15, MTH2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NV35 (0-163)
      • engineered mutation (138)
  • Heterogens: SYW, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7b65A (A:)
mtasaqprgrrpgvgvgvvvtsckhprcvllgkrkgsvgagsfqlpgghlefgetweeca
qretweeaalhlknvhfasvvnsfiekenyhyvtilmkgevdvthdsepknvepeknesw
ewvpweelppldqlfwglcclkeqgydpfkedlnhlvgykgnhl

    Sequence, based on observed residues (ATOM records):
    >7b65A (A:)
rpgvgvgvvvtsckhprcvllgkrkgsvgagsfqlpgghlefgetweecaqretweeaal
hlknvhfasvvnsfiekenyhyvtilmkgevdvthdsepknvepekneswewvpweelpp
ldqlfwglcclkeqgydpfkedlnhlvgykgnhl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7b65B (B:)
mtasaqprgrrpgvgvgvvvtsckhprcvllgkrkgsvgagsfqlpgghlefgetweeca
qretweeaalhlknvhfasvvnsfiekenyhyvtilmkgevdvthdsepknvepeknesw
ewvpweelppldqlfwglcclkeqgydpfkedlnhlvgykgnhl

    Sequence, based on observed residues (ATOM records):
    >7b65B (B:)
rpgvgvgvvvtsckhprcvllgkrkgsvgagsfqlpgghlefgetweecaqretweeaal
hlknvhfasvvnsfiekenyhyvtilmkgevdvthdsepknvepekneswewvpweelpp
ldqlfwglcclkeqgydpfkedlnhlvgykgnhl