PDB entry 7b57

View 7b57 on RCSB PDB site
Description: Crystal structure of CaMKII-actinin complex bound to ADP
Class: structural protein
Keywords: CaMKII, actinin, dendritic spine, STRUCTURAL PROTEIN
Deposited on 2020-12-03, released 2022-06-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-06-22, with a file datestamp of 2022-06-17.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-actinin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTN2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35609 (3-72)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7b57a_
  • Chain 'B':
    Compound: Calcium/calmodulin-dependent protein kinase type II subunit alpha
    Species: Mus musculus [TaxId:10090]
    Gene: CAMK2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11798 (2-316)
      • expression tag (0-1)
      • engineered mutation (306-307)
    Domains in SCOPe 2.08: d7b57b_
  • Heterogens: ADP, MES, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >7b57A (A:)
    snatdtaeqviasfrilasdkpyilaeelrrelppdqaqycikrmpaysgpgsvpgaldy
    aafssalygesdl
    

    Sequence, based on observed residues (ATOM records): (download)
    >7b57A (A:)
    taeqviasfrilasdkpyilaeelrrelppdqaqycikrmpaysgpgsvpgaldyaafss
    aly
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >7b57B (B:)
    smmatitctrfteeyqlfeelgkgafsvvrrcvkvlagqeyaakiintkklsardhqkle
    rearicrllkhpnivrlhdsiseeghhylifdlvtggelfedivareyyseadashciqq
    ileavlhchqmgvvhrdlkpenlllasklkgaavkladfglaievegeqqawfgfagtpg
    ylspevlrkdpygkpvdlwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewd
    tvtpeakdlinkmltinpskritaaealkhpwishrstvascmhrqetvdclkkfnarrk
    lkgailaamlatrnfsg
    

    Sequence, based on observed residues (ATOM records): (download)
    >7b57B (B:)
    tctrfteeyqlfeelgkgafsvvrrcvkvlagqeyaakiintkklsardhqklerearic
    rllkhpnivrlhdsiseeghhylifdlvtggelfedivareyyseadashciqqileavl
    hchqmgvvhrdlkpenlllasklkgaavkladfglaievegeqqawfgfagtpgylspev
    lrkdpygkpvdlwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpea
    kdlinkmltinpskritaaealkhpwishrstvascmhrqetvdclkkfnarrklkgail
    aam