PDB entry 7b3o

View 7b3o on RCSB PDB site
Description: Crystal structure of the SARS-CoV-2 RBD in complex with STE90-C11 Fab
Class: antiviral protein
Keywords: neutralizing antibodies, SARS-CoV-2, RBD, ANTIVIRAL PROTEIN
Deposited on 2020-12-01, released 2020-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'E':
    Compound: Spike protein S1
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2 (2-195)
      • initiating methionine (0)
      • expression tag (1)
      • expression tag (196-204)
    Domains in SCOPe 2.08: d7b3oe_
  • Chain 'H':
    Compound: heavy chain of Fab fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7B3O (0-227)
    Domains in SCOPe 2.08: d7b3oh_
  • Chain 'L':
    Compound: light chain of Fab fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7B3O (0-214)
    Domains in SCOPe 2.08: d7b3ol1, d7b3ol2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7b3oE (E:)
manitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkln
dlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggn
ynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpy
rvvvlsfellhapatvaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7b3oE (E:)
lcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftn
vyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyr
lfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrvvvls
fel

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >7b3oH (H:)
qvqlvesggglvqpggslrlscaasgltvssnymswvrqapgkglewvsviysggstyya
dsvkgrftisrddskntlylqmnslraedtavyycardvadafdiwgqgtmvtvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7b3oH (H:)
qvqlvesggglvqpggslrlscaasgltvssnymswvrqapgkglewvsviysggstyya
dsvkgrftisrddskntlylqmnslraedtavyycardvadafdiwgqgtmvtvssastk
gpsvfplapsskgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7b3oL (L:)
divmtqspsflsasvgdrvtitcrasqgissylawyqqkpgkapklliyaastlqsgvps
rfsgsgsgteftltisslqpedfatyycqqlnsyppftfgpgtkvdikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglrspvtksfnrgec