PDB entry 7b32

View 7b32 on RCSB PDB site
Description: MST3 in complex with MRIA7
Class: transferase
Keywords: kinase inhibitors, structure-based drug design, SIK2 inhibitor, Structural Genomics Consortium, SGC, transferase
Deposited on 2020-11-28, released 2020-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-07, with a file datestamp of 2021-07-02.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase 24
    Species: Homo sapiens [TaxId:9606]
    Gene: STK24, MST3, STK3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y6E0 (1-298)
      • initiating methionine (0)
      • expression tag (299-305)
    Domains in SCOPe 2.08: d7b32a1, d7b32a2
  • Heterogens: SQQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7b32A (A:)
mraqlwglalnkrratlphpggstnlkadpeelftklekigkgsfgevfkgidnrtqkvv
aikiidleeaedeiediqqeitvlsqcdspyvtkyygsylkdtklwiimeylgggsaldl
lepgpldetqiatilreilkgldylhsekkihrdikaanvllsehgevkladfgvagqlt
dtqikrntfvgtpfwmapevikqsaydskadiwslgitaielargepphselhpmkvlfl
ipknnpptlegnyskplkefveaclnkepsfrptakellkhkfilrnakktsyltelida
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7b32A (A:)
tnlkadpeelftklekigkgsfgevfkgidnrtqkvvaikiidleeaedeiediqqeitv
lsqcdspyvtkyygsylkdtklwiimeylgggsaldllepgpldetqiatilreilkgld
ylhsekkihrdikaanvllsehgevkladfgvatpfwmapevikqydskadiwslgitai
elargepphselhpmkvlflipknnpptlegnyskplkefveaclnkepsfrptakellk
hkfilrnakktsyltelidahhhh