PDB entry 7b1h

View 7b1h on RCSB PDB site
Description: monoclinic p21 structure of human mad1 c-terminal domain in complex with phosphorylated bub1 cd1 domain
Deposited on 2020-11-24, released 2021-03-17
The last revision was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitotic spindle assembly checkpoint protein MAD1
    Species: Homo sapiens [TaxId:9606]
    Gene: MAD1L1, MAD1, TXBP181
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Mitotic spindle assembly checkpoint protein MAD1
    Species: Homo sapiens [TaxId:9606]
    Gene: MAD1L1, MAD1, TXBP181
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Mitotic checkpoint serine/threonine-protein kinase BUB1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43683 (0-24)
      • expression tag (25)
  • Chain 'D':
    Compound: Mitotic checkpoint serine/threonine-protein kinase BUB1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43683 (0-24)
      • expression tag (25)
  • Chain 'E':
    Compound: Mitotic spindle assembly checkpoint protein MAD1
    Species: Homo sapiens [TaxId:9606]
    Gene: MAD1L1, MAD1, TXBP181
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Mitotic spindle assembly checkpoint protein MAD1
    Species: Homo sapiens [TaxId:9606]
    Gene: MAD1L1, MAD1, TXBP181
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Mitotic checkpoint serine/threonine-protein kinase BUB1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43683 (0-24)
      • expression tag (25)
  • Chain 'H':
    Compound: Mitotic checkpoint serine/threonine-protein kinase BUB1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43683 (0-24)
      • expression tag (25)
  • Heterogens: TPO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >7b1hA (A:)
sskevaelkkqvesaelknqrlkevfqtkiqefrkacytltgyqidittenqyrltslya
ehpgdclifkatspsgskmqlletefshtvgelievhlrrqdsipaflssltlelfsrqt
va

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >7b1hB (B:)
sskevaelkkqvesaelknqrlkevfqtkiqefrkacytltgyqidittenqyrltslya
ehpgdclifkatspsgskmqlletefshtvgelievhlrrqdsipaflssltlelfsrqt
va

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7b1hC (C:)
kvqpsptvhtkealgfimnmfqapts

    Sequence, based on observed residues (ATOM records):
    >7b1hC (C:)
ptvhtkealgfimnmfqa

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7b1hD (D:)
kvqpsptvhtkealgfimnmfqapts

    Sequence, based on observed residues (ATOM records):
    >7b1hD (D:)
ptvhtkealgfimnmfqapt

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records:
    >7b1hE (E:)
sskevaelkkqvesaelknqrlkevfqtkiqefrkacytltgyqidittenqyrltslya
ehpgdclifkatspsgskmqlletefshtvgelievhlrrqdsipaflssltlelfsrqt
va

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >7b1hF (F:)
sskevaelkkqvesaelknqrlkevfqtkiqefrkacytltgyqidittenqyrltslya
ehpgdclifkatspsgskmqlletefshtvgelievhlrrqdsipaflssltlelfsrqt
va

  • Chain 'G':
    Sequence, based on SEQRES records:
    >7b1hG (G:)
kvqpsptvhtkealgfimnmfqapts

    Sequence, based on observed residues (ATOM records):
    >7b1hG (G:)
ptvhtkealgfimnmfqa

  • Chain 'H':
    Sequence, based on SEQRES records:
    >7b1hH (H:)
kvqpsptvhtkealgfimnmfqapts

    Sequence, based on observed residues (ATOM records):
    >7b1hH (H:)
ptvhtkealgfimnmfqapts