PDB entry 7b1f

View 7b1f on RCSB PDB site
Description: orthorhombic p212121 structure of human mad1 c-terminal domain in complex with phosphorylated bub1 cd1 domain
Deposited on 2020-11-24, released 2021-03-17
The last revision was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitotic spindle assembly checkpoint protein MAD1
    Species: Homo sapiens [TaxId:9606]
    Gene: MAD1L1, MAD1, TXBP181
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Mitotic spindle assembly checkpoint protein MAD1
    Species: Homo sapiens [TaxId:9606]
    Gene: MAD1L1, MAD1, TXBP181
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Mitotic checkpoint serine/threonine-protein kinase BUB1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43683 (0-24)
      • expression tag (25)
  • Chain 'D':
    Compound: Mitotic checkpoint serine/threonine-protein kinase BUB1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43683 (0-24)
      • expression tag (25)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >7b1fA (A:)
sskevaelkkqvesaelknqrlkevfqtkiqefrkacytltgyqidittenqyrltslya
ehpgdclifkatspsgskmqlletefshtvgelievhlrrqdsipaflssltlelfsrqt
va

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7b1fB (B:)
sskevaelkkqvesaelknqrlkevfqtkiqefrkacytltgyqidittenqyrltslya
ehpgdclifkatspsgskmqlletefshtvgelievhlrrqdsipaflssltlelfsrqt
va

    Sequence, based on observed residues (ATOM records):
    >7b1fB (B:)
sskevaelkkqvesaelknqrlkevfqtkiqefrkacytltgyqidittenqyrltslya
ehpgdclifkatskmqlletefshtvgelievhlrrqdsipaflssltlelfsrqtva

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7b1fC (C:)
kvqpsptvhtkealgfimnmfqapts

    Sequence, based on observed residues (ATOM records):
    >7b1fC (C:)
qpsptvhtkealgfimnmfqa

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7b1fD (D:)
kvqpsptvhtkealgfimnmfqapts

    Sequence, based on observed residues (ATOM records):
    >7b1fD (D:)
qpsptvhtkealgfimnmfqa