PDB entry 7axk

View 7axk on RCSB PDB site
Description: Crystal structure of the hPXR-LBD in complex with estradiol and endosulfan
Class: nuclear protein
Keywords: nuclear receptor hormone receptor pregnane x receptor, nuclear protein
Deposited on 2020-11-09, released 2021-01-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-13, with a file datestamp of 2021-01-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor subfamily 1 group I member 2
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1I2, PXR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7axka_
  • Heterogens: S68, EST, MPD, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7axkA (A:)
mkkghhhhhhgsertgtqplgvqglteeqrmmirelmdaqmktfdttfshfknfrlpgvl
ssgcelpeslqapsreeaakwsqvrkdlcslkvslqlrgedgsvwnykppadsggkeifs
llphmadmstymfkgiisfakvisyfrdlpiedqisllkgaafelcqlrfntvfnaetgt
wecgrlsycledtaggfqqlllepmlkfhymlkklqlheeeyvlmqaislfspdrpgvlq
hrvvdqlqeqfaitlksyiecnrpqpahrflflkimamltelrsinaqhtqrllriqdih
pfatplmqelfgitgs

    Sequence, based on observed residues (ATOM records): (download) 
    >7axkA (A:)
glteeqrmmirelmdaqmktfdttfshfknfrlpgveaakwsqvrkdlcslkvslqlrge
dgsvwnykppadsggkeifsllphmadmstymfkgiisfakvisyfrdlpiedqisllkg
aafelcqlrfntvfnaetgtwecgrlsycledfqqlllepmlkfhymlkklqlheeeyvl
mqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrpqpahrflflkimamltelrs
inaqhtqrllriqdihpfatplmqelfgitgs