PDB entry 7aw6

View 7aw6 on RCSB PDB site
Description: the extracellular region of cd33 with bound sialoside analogue p22
Deposited on 2020-11-06, released 2020-12-16
The last revision was dated 2020-12-16, with a file datestamp of 2020-12-11.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Myeloid cell surface antigen CD33
    Species: Homo sapiens [TaxId:9606]
    Gene: CD33, SIGLEC3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20138 (31-242)
      • expression tag (30)
  • Chain 'B':
    Compound: Myeloid cell surface antigen CD33
    Species: Homo sapiens [TaxId:9606]
    Gene: CD33, SIGLEC3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20138 (31-242)
      • expression tag (29-30)
  • Heterogens: FVP, NAG, PO4, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7aw6A (A:)
    mgilpspgmpallslvsllsvllmgcvaetgfwlqvqesvtvqeglcvlvpctffhpipy
    ydknspvhgywfregaiisrdspvatnkldqevqeetqgrfrllgdpsrnncslsivdar
    rrdngsyffrmergstkysykspqlsvhvtdlthrpkilipgtlepghsknltcsvswac
    eqgtppifswlsaaptslgprtthssvliitprpqdhgtnltcqvkfagagvttertiql
    nvtgtkhhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >7aw6A (A:)
    gfwlqvqesvtvqeglcvlvpctffhpipyydknspvhgywfregaiisrdspvatnkld
    qevqeetqgrfrllgdpsrnncslsivdarrrdngsyffrmergstkysykspqlsvhvt
    dlthrpkilipgtlepghsknltcsvswaceqgtppifswlsaaptslgprtthssvlii
    tprpqdhgtnltcqvkfagagvttertiqlnvt
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7aw6B (B:)
    mgilpspgmpallslvsllsvllmgcvaetgfwlqvqesvtvqeglcvlvpctffhpipy
    ydknspvhgywfregaiisrdspvatnkldqevqeetqgrfrllgdpsrnncslsivdar
    rrdngsyffrmergstkysykspqlsvhvtdlthrpkilipgtlepghsknltcsvswac
    eqgtppifswlsaaptslgprtthssvliitprpqdhgtnltcqvkfagagvttertiql
    nvtgtkhhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >7aw6B (B:)
    tgfwlqvqesvtvqeglcvlvpctffhpipyydknspvhgywfregaiisrdspvatnkl
    dqevqeetqgrfrllgdpsrnncslsivdarrrdngsyffrmergstkysykspqlsvhv
    tdlthrpkilipgtlepghsknltcsvswaceqgtppifswlsaaptslgprtthssvli
    itprpqdhgtnltcqvkfagagvttertiqlnvt