PDB entry 7aqx

View 7aqx on RCSB PDB site
Description: Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB9)
Class: membrane protein
Keywords: Variant surface Glycoprotein, Epitope Mapping, Immune Evasion, Membrane Protein
Deposited on 2020-10-23, released 2021-11-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-11-03, with a file datestamp of 2021-10-29.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: variant surface glycoprotein mitat 1.2
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7aqxa_
  • Chain 'B':
    Compound: variant surface glycoprotein mitat 1.2
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7aqxb_
  • Chain 'C':
    Compound: Nanobody VSG2(NB9)
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 7AQX (0-141)
    Domains in SCOPe 2.08: d7aqxc1, d7aqxc2
  • Chain 'D':
    Compound: Nanobody VSG2(NB9)
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 7AQX (0-141)
    Domains in SCOPe 2.08: d7aqxd1, d7aqxd2
  • Heterogens: CIT, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7aqxA (A:)
aaekgfkqafwqplcqvseelddqpkgalftlqaaaskiqkmrdaalrasiyaeinhgtn
rakaavivanhyamkadsglealkqtlssqevtatatasylkgrideylnlllqtkesgt
sgcmmdtsgtntvtkaggtiggvpcklqlspiqpkrpaatylgkagyvgltrqadaannf
hdndaecrlasghntnglgksgqlsaavtmaagyvtvansqtavtvqaldalqeasgaah
qpwidawkakkaltgaetaefrnetagiagktgvtklveeallkkkdseaseiqtelkky
fsgheneqwtaiekliseqpvaqnlvgdnqptklgelegnaklttilayyrmetagkfev
ltqk

    Sequence, based on observed residues (ATOM records): (download) 
    >7aqxA (A:)
aaekgfkqafwqplcqvseelddqpkgalftlqaaaskiqkmrdaalrasiyaeinhgtn
rakaavivanhyamkadsglealkqtlssqevtatatasylkgrideylnlllqtkesgt
sgcmmdtsgtntvtkaggtiggvpcklqlspiqpkrpaatylgkagyvgltrqadaannf
hdndaecrlasghntnglgksgqlsaavtmaagyvtvansqtavtvqaldalqeasgaah
qpwidawkakkaltgaetaefrnetagiagktgvtklveeallkkkdseaseiqtelkky
fsgheneqwtaiekliseqpvaqnlvgdnqptklgelegnaklttilayyrmetagkfev
lt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7aqxB (B:)
aaekgfkqafwqplcqvseelddqpkgalftlqaaaskiqkmrdaalrasiyaeinhgtn
rakaavivanhyamkadsglealkqtlssqevtatatasylkgrideylnlllqtkesgt
sgcmmdtsgtntvtkaggtiggvpcklqlspiqpkrpaatylgkagyvgltrqadaannf
hdndaecrlasghntnglgksgqlsaavtmaagyvtvansqtavtvqaldalqeasgaah
qpwidawkakkaltgaetaefrnetagiagktgvtklveeallkkkdseaseiqtelkky
fsgheneqwtaiekliseqpvaqnlvgdnqptklgelegnaklttilayyrmetagkfev
ltqk

    Sequence, based on observed residues (ATOM records): (download) 
    >7aqxB (B:)
aaekgfkqafwqplcqvseelddqpkgalftlqaaaskiqkmrdaalrasiyaeinhgtn
rakaavivanhyamkadsglealkqtlssqevtatatasylkgrideylnlllqtkesgt
sgcmmdtsgtntvtkaggtiggvpcklqlspiqpkrpaatylgkagyvgltrqadaannf
hdndaecrlasghntnglgksgqlsaavtmaagyvtvansqtavtvqaldalqeasgaah
qpwidawkakkaltgaetaefrnetagiagktgvtklveeallkkkdseaseiqtelkky
fsgheneqwtaiekliseqpvaqnlvgdnqptklgelegnaklttilayyrmetagkfev
lt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7aqxC (C:)
qvqlqesggglvqaggslrlscttsgltfsnyafswfrqapgeerefvgaiswsggrtdy
adsvkgrftisrdnakntfylqmnslktedtavyycaadllgegsrrseyeywgqgtqvt
vssaaaypydvpdygshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7aqxC (C:)
qvqlqesggglvqaggslrlscttsgltfsnyafswfrqarefvgaiswsggrtdyadsv
kgrftisrdnakntfylqmnslkedtavyycaadllgegsrrseyeywgqgtqvtv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7aqxD (D:)
qvqlqesggglvqaggslrlscttsgltfsnyafswfrqapgeerefvgaiswsggrtdy
adsvkgrftisrdnakntfylqmnslktedtavyycaadllgegsrrseyeywgqgtqvt
vssaaaypydvpdygshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7aqxD (D:)
vqlqesglrlscttsgltfsnyafswfrqrefvgaiswsggrtdyasvkgrftisrdnak
ntfylqmnsldtavyycaadllgegsrrseyeywgqgtq