PDB entry 7aqu

View 7aqu on RCSB PDB site
Description: flavin-dependent tryptophan halogenase thal: n-terminally his-tagged form of quintuple mutant (nhis-thal-rebh5)
Deposited on 2020-10-23, released 2020-12-23
The last revision was dated 2020-12-23, with a file datestamp of 2020-12-18.
Experiment type: XRAY
Resolution: 1.63 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tryptophan 6-halogenase
    Species: Streptomyces albogriseolus [TaxId:1887]
    Gene: thal, thdH
    Database cross-references and differences (RAF-indexed):
    • Uniprot A1E280
      • engineered mutation (71)
      • engineered mutation (101)
      • engineered mutation (379)
      • engineered mutation (488-489)
  • Chain 'B':
    Compound: Tryptophan 6-halogenase
    Species: Streptomyces albogriseolus [TaxId:1887]
    Gene: thal, thdH
    Database cross-references and differences (RAF-indexed):
    • Uniprot A1E280
      • engineered mutation (71)
      • engineered mutation (101)
      • engineered mutation (379)
      • engineered mutation (488-489)
  • Heterogens: BCN, GOL, GLY, ALA, SER, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7aquA (A:)
mgsshhhhhhssglvprgshmdnriktvvilgggtagwmtaaylgkalqntvkivvleap
tiprigvgeatipnlqraffdylgipeeewmrecnasykmaikfinwrtpgegspdprtl
ddghtdtfhhpfgllpsadqiplshywaakrlqgetdenfdeacfadtaimnakkaprfl
dmrratnyawhfdaskvaaflrnfavtkqavehvedemtevltdergfitalrtksgril
qgdlfvdcsgfrgllinkameepfidmsdhllcnsavatavphddekngvepytssiame
agwtwkipmlgrfgsghvysdhfatqdeatlafsklwgldpdntefnhvrfrvgrnrraw
vrncvsvglascfveplestgiyfiyaaihmlakhfpdktfdkvlvdrfnreieemfddt
rdflqahyyfsprvdtpfwrankelkladsikdkvetyraglpvnlpvtdegtyygnfea
efrnfwtnsnyycifaglglmprnplpalaykpqsiaeaellfadvkrkgdtlveslpst
ydllrqlhgas

    Sequence, based on observed residues (ATOM records):
    >7aquA (A:)
dnriktvvilgggtagwmtaaylgkalqntvkivvleapigvgeatipnlqraffdylgi
peeewmrecnasykmaikfinwrtpgegspdprtlddghtdtfhhpfgllpsadqiplsh
ywaakrlqgetdenfdeacfadtaimnakkaprfldmrratnyawhfdaskvaaflrnfa
vtkqavehvedemtevltdergfitalrtksgrilqgdlfvdcsgfrgllinkameepfi
dmsdhllcnsavatavphddekngvepytssiameagwtwkipmlgrfgsghvysdhfat
qdeatlafsklwgldpdntefnhvrfrvgrnrrawvrncvsvglascfveplestgiyfi
yaaihmlakhfpdktfdkvlvdrfnreieemfddtrdflqahyyfsprvdtpfwrankel
kladsikdkvetyraglpvnlpvtdegtyygnfeaefrnfwtnsnyycifaglglmprnp
lpalaykpqsiaeaellfadvkrkgdtlveslpstydllrqlhga

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7aquB (B:)
mgsshhhhhhssglvprgshmdnriktvvilgggtagwmtaaylgkalqntvkivvleap
tiprigvgeatipnlqraffdylgipeeewmrecnasykmaikfinwrtpgegspdprtl
ddghtdtfhhpfgllpsadqiplshywaakrlqgetdenfdeacfadtaimnakkaprfl
dmrratnyawhfdaskvaaflrnfavtkqavehvedemtevltdergfitalrtksgril
qgdlfvdcsgfrgllinkameepfidmsdhllcnsavatavphddekngvepytssiame
agwtwkipmlgrfgsghvysdhfatqdeatlafsklwgldpdntefnhvrfrvgrnrraw
vrncvsvglascfveplestgiyfiyaaihmlakhfpdktfdkvlvdrfnreieemfddt
rdflqahyyfsprvdtpfwrankelkladsikdkvetyraglpvnlpvtdegtyygnfea
efrnfwtnsnyycifaglglmprnplpalaykpqsiaeaellfadvkrkgdtlveslpst
ydllrqlhgas

    Sequence, based on observed residues (ATOM records):
    >7aquB (B:)
dnriktvvilgggtagwmtaaylgkalqntvkivvleaptiprigvgeatipnlqraffd
ylgipeeewmrecnasykmaikfinwrtpgegspdprtlddghtdtfhhpfgllpsadqi
plshywaakrlqgetdenfdeacfadtaimnakkaprfldmrratnyawhfdaskvaafl
rnfavtkqavehvedemtevltdergfitalrtksgrilqgdlfvdcsgfrgllinkame
epfidmsdhllcnsavatavphddekngvepytssiameagwtwkipmlgrfgsghvysd
hfatqdeatlafsklwgldpdntefnhvrfrvgrnrrawvrncvsvglascfveplestg
iyfiyaaihmlakhfpdktfdkvlvdrfnreieemfddtrdflqahyyfsprvdtpfwra
nkelkladsikdkvetyraglpvnlpgtyynfeaefrnfwtnsnyycifaglglmprnpl
palaykpqsiaeaellfadvkrkgdtlveslpstydllrqlhg