PDB entry 7aq1

View 7aq1 on RCSB PDB site
Description: crystal structure of human mature meprin beta in complex with the specific inhibitor mwt-s-270
Deposited on 2020-10-20, released 2021-03-03
The last revision was dated 2021-06-16, with a file datestamp of 2021-06-11.
Experiment type: XRAY
Resolution: 2.41 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Meprin B subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: MEP1B
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Meprin B subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: MEP1B
    Database cross-references and differences (RAF-indexed):
  • Heterogens: RUE, ZN, EDO, CA, CL, NAG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7aq1A (A:)
nsiigekyrwphtipyvledslemnakgvilnaferyrlktcidfkpwagetnyisvfkg
sgcwssvgnrrvgkqelsigancdriatvqheflhalgfwheqsrsdrddyvrimwdril
sgrehnfntysddisdslnvpydytsvmhysktafqngteptivtrisdfedvigqrmdf
sdsdllklnqlyncssslsfmdscsfelenvcgmiqssgdnadwqrvsqvprgpesdhsn
mgqcqgsgffmhfdsssvnvgatavlesrtlypkrgfqclqfylynsgsesdqlniyire
ysadnvdgnltlveeikeiptgswqlyhvtlkvtkkfrvvfegrkgsgaslgglsiddin
lsetrcphhiwhirnftqfigspngtlysppfysskgyafqiylnlahvtnagiyfhlis
ganddqlqwpcpwqqatmtlldqnpdirqrmsnqrsittdpfmttdngnyfwdrpskvgt
valfsngtqfrrgggygtsafitherlksrdfikgddvyilltvedishlnstq

    Sequence, based on observed residues (ATOM records):
    >7aq1A (A:)
nsiigekyrwphtipyvledslemnakgvilnaferyrlktcidfkpwagetnyisvfkg
sgcwssvgnrrvgkqelsigancdriatvqheflhalgfwheqsrsdrddyvrimwdril
sgrehnfntysddisdslnvpydytsvmhysktafqngteptivtrisdfedvigqrmdf
sdsdllklnqlyncssslsfmdscsfelenvcgmiqssgdnadwqrvsqvprgpesdhsn
mgqcqgsgffmhfdsssvnvgatavlesrtlypkrgfqclqfylynsgsesdqlniyire
ysadnvdgnltlveeikeiptgswqlyhvtlkvtkkfrvvfegrkgsgaslgglsiddin
lsetrcphhiwhirnftqfigspngtlysppfysskgyafqiylnlahvtnagiyfhlis
ganddqlqwpcpwqqatmtlldqnpdirqrmsnqrsittdpfmttdngnyfwdrpskvgt
valfsngtqfrrgggygtsafitherlksrdfikgddvyilltvedishlnst

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7aq1B (B:)
nsiigekyrwphtipyvledslemnakgvilnaferyrlktcidfkpwagetnyisvfkg
sgcwssvgnrrvgkqelsigancdriatvqheflhalgfwheqsrsdrddyvrimwdril
sgrehnfntysddisdslnvpydytsvmhysktafqngteptivtrisdfedvigqrmdf
sdsdllklnqlyncssslsfmdscsfelenvcgmiqssgdnadwqrvsqvprgpesdhsn
mgqcqgsgffmhfdsssvnvgatavlesrtlypkrgfqclqfylynsgsesdqlniyire
ysadnvdgnltlveeikeiptgswqlyhvtlkvtkkfrvvfegrkgsgaslgglsiddin
lsetrcphhiwhirnftqfigspngtlysppfysskgyafqiylnlahvtnagiyfhlis
ganddqlqwpcpwqqatmtlldqnpdirqrmsnqrsittdpfmttdngnyfwdrpskvgt
valfsngtqfrrgggygtsafitherlksrdfikgddvyilltvedishlnstq

    Sequence, based on observed residues (ATOM records):
    >7aq1B (B:)
nsiigekyrwphtipyvledslemnakgvilnaferyrlktcidfkpwagetnyisvfkg
sgcwssvgnrrvgkqelsigancdriatvqheflhalgfwheqsrsdrddyvrimwdril
sgrehnfntysddisdslnvpydytsvmhysktafqngteptivtrisdfedvigqrmdf
sdsdllklnqlyncssslsfmdscsfelenvcgmiqssgdnadwqrvsqvprgpesdhsn
mgqcqgsgffmhfdsssvnvgatavlesrtlypkrgfqclqfylynsgsesdqlniyire
ysadnvdgnltlveeikeiptgswqlyhvtlkvtkkfrvvfegrkgsgaslgglsiddin
lsetrcphhiwhirnftqfigspngtlysppfysskgyafqiylnlahvtnagiyfhlis
ganddqlqwpcpwqqatmtlldqnpdirqrmsnqrsittdpfmttdngnyfwdrpskvgt
valfsngtqfrrgggygtsafitherlksrdfikgddvyilltvedishlnst