PDB entry 7akm

View 7akm on RCSB PDB site
Description: Crystal structure of CHK1 kinase domain in complex with ATPyS
Class: cell cycle
Keywords: cell cycle
Deposited on 2020-10-01, released 2021-04-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-16, with a file datestamp of 2021-06-11.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase Chk1
    Species: Homo sapiens [TaxId:9606]
    Gene: CHEK1, CHK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14757 (4-End)
      • engineered mutation (12)
    Domains in SCOPe 2.08: d7akma_
  • Chain 'B':
    Compound: Serine/threonine-protein kinase Chk1
    Species: Homo sapiens [TaxId:9606]
    Gene: CHEK1, CHK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14757 (4-End)
      • engineered mutation (12)
    Domains in SCOPe 2.08: d7akmb_
  • Heterogens: AGS, MG, EDO, CIT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7akmA (A:)
gpgsavpfvedwrlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeic
inkmlnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmag
vvylhgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvape
llkrrefhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsa
plallhkilvenpsaritipdikkdrwynkplkkgakrprvtsggvsesphhhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7akmA (A:)
avpfvedwrlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkm
lnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvyl
hgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkr
refhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplal
lhkilvenpsaritipdikkdrwynkplkk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7akmB (B:)
gpgsavpfvedwrlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeic
inkmlnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmag
vvylhgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvape
llkrrefhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsa
plallhkilvenpsaritipdikkdrwynkplkkgakrprvtsggvsesphhhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7akmB (B:)
avpfvedwrlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkm
lnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvyl
hgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkr
refhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplal
lhkilvenpsaritipdikkdrwynkpl