PDB entry 7akg

View 7akg on RCSB PDB site
Description: Crystal structure of STK17B with bound dovitinib
Class: transferase
Keywords: kinase, STK17B, inhibitor, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2020-09-30, released 2020-12-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-13, with a file datestamp of 2021-01-08.
Experiment type: XRAY
Resolution: 2.08 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase 17B
    Species: Homo sapiens [TaxId:9606]
    Gene: STK17B, DRAK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O94768 (22-End)
      • expression tag (14-21)
    Domains in SCOPe 2.08: d7akga1, d7akga2
  • Heterogens: 38O, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7akgA (A:)
mhhhhhhssgvdlgtenlyfqsmenfnnfyiltskelgrgkfavvrqciskstgqeyaak
flkkrrrgqdcraeilheiavlelakscprvinlhevyentseiilileyaaggeifslc
lpelaemvsendvirlikqilegvyylhqnnivhldlkpqnillssiyplgdikivdfgm
srkighacelreimgtpeylapeilnydpittatdmwnigiiaymllthtspfvgednqe
tylnisqvnvdyseetfssvsqlatdfiqsllvknpekrptaeiclshswlqqwdfenlf
hpeetssssqtqdhsvrssedktskss

    Sequence, based on observed residues (ATOM records): (download) 
    >7akgA (A:)
tenlyfqsmenfnnfyiltskelgrgkfavvrqciskstgqeyaakflkkrrrgqdcrae
ilheiavlelakscprvinlhevyentseiilileyaaggeifslclpelaemvsendvi
rlikqilegvyylhqnnivhldlkpqnillssiyplgdikivdfgmsrkighacelreim
gtpeylapeilnydpittatdmwnigiiaymllthtspfvgednqetylnisqvnvdyse
etfssvsqlatdfiqsllvknpekrptaeiclshswlqqwdfenlfhpeetss